{"id":"W3177186401","doi":"10.1183/23120541.00107-2021","title":"Development and validation of a mouse model of contemporary cannabis smoke exposure","year":2021,"lang":"en","type":"article","venue":"ERJ Open Research","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Health Canada; Lung Health Foundation; McMaster University","keywords":"Cannabis; Medicine; Lung; Immune system; Cannabinoid; Immunology; Smoke; Chemokine; Dronabinol; Cannabidiol; COPD; Macrophage; Effects of cannabis; Cannabinoid receptor; Pharmacology; Alveolar macrophage; Physiology; Receptor; Internal medicine; Biology; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002122985,0.001746406,0.001069297,0.003360193,0.001042622,0.001347747,0.001502072,0.002657932,0.004780628],"category_scores_gemma":[0.0009537943,0.001045477,0.001500335,0.0006768923,0.001335452,0.001283792,0.001141485,0.003652952,0.002156012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000898515,"about_ca_system_score_gemma":0.0009534699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001526161,"about_ca_topic_score_gemma":0.002773309,"domain_scores_codex":[0.9976623,0.0003476103,0.0003077247,0.0006292281,0.0007003004,0.000352877],"domain_scores_gemma":[0.9981238,0.0002688285,0.0003935929,0.0003433322,0.0003987768,0.0004717271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009725793,0.001379076,0.001462282,0.0002252808,0.00007057725,0.0004191064,0.0002560739,0.0003968763,0.9873238,0.001196383,0.0004789445,0.005819074],"study_design_scores_gemma":[0.0005228997,0.01077549,0.01561922,0.0003367245,0.0004448118,0.002387296,0.0005880605,0.004430437,0.9325071,0.001071339,0.03118459,0.0001320127],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8971432,0.004548004,0.07514209,0.00148147,0.0008494798,0.002999395,0.008861636,0.00142984,0.007544803],"genre_scores_gemma":[0.842117,0.007641748,0.08675221,0.001343454,0.000234289,0.008290175,0.01341307,0.0007424454,0.03946562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004780628,"threshold_uncertainty_score":0.01599276,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2026182009795299,"score_gpt":0.4161889872458792,"score_spread":0.2135707862663492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}