{"id":"W3177361042","doi":"10.2337/db21-1161-p","title":"1161-P: NOD1-JNK1 Axis Plays a Causal Role in Palmitate-Induced ß-Cell Dysfunction","year":2021,"lang":"en","type":"article","venue":"Diabetes","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"NOD1; Endocrinology; Internal medicine; Receptor; Nod; In vivo; Cell; Chemistry; Biology; Innate immune system; Medicine; Diabetes mellitus; Biochemistry; NOD2","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002995518,0.000893369,0.0004906745,0.0004041618,0.0004236193,0.0005421064,0.0003638221,0.0006905345,0.006549777],"category_scores_gemma":[0.0001872171,0.0002808443,0.0006720953,0.0002448609,0.000458072,0.0004037048,0.0006509626,0.001490697,0.00160389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003242719,"about_ca_system_score_gemma":0.0003093725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003343513,"about_ca_topic_score_gemma":0.000310195,"domain_scores_codex":[0.9997064,0.00004493893,0.00003223245,0.00008319857,0.00005326476,0.00007992404],"domain_scores_gemma":[0.9997508,0.000009460434,0.0000915644,0.00001442523,0.00003027723,0.0001034921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00441684,0.0002928685,0.006624872,0.001240238,0.0001277897,0.00197975,0.0001142407,0.0001543924,0.9702018,0.001068612,0.001462716,0.01231595],"study_design_scores_gemma":[0.0008960738,0.002712966,0.2263807,0.000359017,0.0006465298,0.01287532,0.0008013392,0.003452585,0.7089388,0.003037007,0.03980066,0.00009902887],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9612281,0.01774,0.00703716,0.00169157,0.0006419404,0.0001614988,0.002594462,0.0004377822,0.008467487],"genre_scores_gemma":[0.981445,0.004828554,0.001989432,0.0003796612,0.0001359774,0.0001870536,0.001673124,0.00004269636,0.009318485],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006549777,"threshold_uncertainty_score":0.0219112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01199880519338904,"score_gpt":0.2345439036235947,"score_spread":0.2225450984302057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}