{"id":"W3177439232","doi":"10.1210/jendso/bvaa046.1907","title":"MON-323 IGF-I Variability and Its Association with Demographic and Clinical Characteristics in Patients with Acromegaly Treated with Injectable Somatostatin Receptor Ligands (SRLS); Results from an International Prospective Phase III Study","year":2020,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Pituitary Gland Disorders and Treatments","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; University of British Columbia Hospital","funders":"","keywords":"Acromegaly; Medicine; Octreotide; Somatostatin; Internal medicine; Concomitant; Prospective cohort study; Population; Randomization; Demographics; Endocrinology; Clinical trial; Demography; Growth hormone; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001282211,0.0003908575,0.0004869885,0.0003278614,0.0002382371,0.0005589853,0.0002115965,0.0003125797,0.0007744621],"category_scores_gemma":[0.001110796,0.0001803646,0.0005114114,0.0004423477,0.0002695681,0.0003274263,0.0002401776,0.0005757959,0.0002307543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002612217,"about_ca_system_score_gemma":0.000260277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005292996,"about_ca_topic_score_gemma":0.0007472385,"domain_scores_codex":[0.9995329,0.0001897726,0.00004450408,0.00009447479,0.00009285995,0.00004540106],"domain_scores_gemma":[0.9985152,0.0003257933,0.0005877902,0.0001315671,0.0001154143,0.0003241856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0314736,0.001479282,0.9479627,0.00006799016,0.0004645522,0.00009480764,0.0001483626,0.0002270421,0.007730167,0.00002153222,0.0002181708,0.0101117],"study_design_scores_gemma":[0.001446204,0.01223022,0.9842474,0.000008456164,0.0001796549,0.0002567899,0.00007989421,0.0004317484,0.0007650179,0.00001505345,0.0003258054,0.00001373117],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991596,0.0002751382,0.00009587055,0.0000117491,0.000003559588,0.00003770103,0.0002138057,0.000004157343,0.0001983951],"genre_scores_gemma":[0.9991754,0.00005846692,0.0001583717,0.00003450809,0.000009588884,0.00004185661,0.0004260527,0.000002197941,0.00009349432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001282211,"threshold_uncertainty_score":0.006781101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016537076412913,"score_gpt":0.2853414033727428,"score_spread":0.2751760326086136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}