{"id":"W3177471654","doi":"10.1038/s41409-021-01386-8","title":"Genetic susceptibility to acute graft versus host disease in pediatric patients undergoing HSCT","year":2021,"lang":"en","type":"article","venue":"Bone Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Alberta Children's Hospital; Centre Hospitalier Universitaire Sainte-Justine","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; National Science Foundation","keywords":"Medicine; Hematopoietic stem cell transplantation; Immunology; Human leukocyte antigen; Graft-versus-host disease; Genetic predisposition; Disease; Stem cell; Cohort; Internal medicine; Antigen; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002238819,0.0004068682,0.0003399687,0.0009412537,0.0005204108,0.0004675364,0.0002909445,0.0004058935,0.002776773],"category_scores_gemma":[0.001783241,0.0001683741,0.0003250541,0.001111198,0.0004980839,0.0002865365,0.0003820682,0.0005284011,0.0001757623],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002872791,"about_ca_system_score_gemma":0.000512797,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003162502,"about_ca_topic_score_gemma":0.002331119,"domain_scores_codex":[0.9996798,0.00009308677,0.00002697476,0.00005755884,0.00006002,0.0000825849],"domain_scores_gemma":[0.9991305,0.0002262559,0.0003671334,0.00003093125,0.00005005521,0.0001951577],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001533389,0.00004504226,0.9951628,0.000008948882,0.00002694775,0.001661789,0.0001736123,0.0000890951,0.000922061,0.00009090141,0.0001078045,0.001557627],"study_design_scores_gemma":[0.00001006514,0.0002335996,0.9907319,0.00001617166,0.00004748961,0.007265657,0.0006525417,0.0002147297,0.0003305442,0.0001210393,0.0003698972,0.000006357875],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999297,0.000104205,0.00005154821,0.00004971006,0.000004492329,0.000003374924,0.0000981803,0.000002470122,0.0003889872],"genre_scores_gemma":[0.9995474,0.0001135764,0.00007768003,0.0000196228,0.00001082478,0.000004662927,0.0001317951,0.000003050214,0.0000913127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003162502,"threshold_uncertainty_score":0.009289205,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01356796927508061,"score_gpt":0.2586801073970539,"score_spread":0.2451121381219733,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}