{"id":"W3177545102","doi":"10.3390/vaccines9070734","title":"Detailed Dissection and Critical Evaluation of the Pfizer/BioNTech and Moderna mRNA Vaccines","year":2021,"lang":"en","type":"article","venue":"Vaccines","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":202,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Messenger RNA; Translation (biology); Untranslated region; Five prime untranslated region; Biology; Ribosome; Genetics; Computational biology; RNA; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001397159,0.00007466401,0.00008400225,0.0000162995,0.00005669014,0.00001787265,0.00005188404,0.00006871948,0.00002227344],"category_scores_gemma":[0.0003044838,0.00005300949,0.0000353642,0.00005435386,0.00001855932,0.000005920191,0.00008634657,0.00003566865,5.321949e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000003469986,"about_ca_system_score_gemma":0.00003859876,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001191666,"about_ca_topic_score_gemma":0.0002446586,"domain_scores_codex":[0.999447,0.00006845572,0.000122034,0.0001897721,0.00009631409,0.00007645477],"domain_scores_gemma":[0.9994257,0.00001520875,0.00003200328,0.0001761159,0.0003269119,0.00002406321],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005006445,0.00002856554,0.05000592,0.00002460034,0.00002828215,4.837789e-7,0.00003554442,0.00001741146,0.9436536,0.00004859139,0.0003178518,0.005789023],"study_design_scores_gemma":[0.0004871167,0.00008535502,0.2053295,0.00003113031,0.00008828482,0.00005912951,0.0001597414,0.001773445,0.7908057,0.0009074585,0.0001821609,0.00009097155],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994754,0.004151612,0.0002036509,0.000507305,0.000153262,0.00007705847,0.000004430656,0.000003527822,0.0001451508],"genre_scores_gemma":[0.9991249,0.0004662183,0.00006381779,0.00006245037,0.00009716956,0.000009203447,0.000008944109,0.000005985102,0.0001612396],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1553236,"threshold_uncertainty_score":0.2161664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02053114566768454,"score_gpt":0.2922492874506792,"score_spread":0.2717181417829946,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}