{"id":"W3177771253","doi":"10.1039/d1cb00123j","title":"<i>In vivo</i> active organometallic-containing antimycotic agents","year":2021,"lang":"en","type":"article","venue":"RSC Chemical Biology","topic":"Synthesis and Biological Evaluation","field":"Chemistry","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Biotechnology and Biological Sciences Research Council; Promedica Stiftung; Universität Zürich; University of Sussex; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Agence Nationale de la Recherche; Provincia Autonoma di Trento; National Science Foundation","keywords":"Fluconazole; In vivo; Antifungal; Drug; Chemistry; Pharmacology; Medicine; Microbiology; Biology; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001143783,0.0001476663,0.0003055091,0.00002195874,0.00002735891,0.00001099745,0.0001542444,0.0003191518,0.017935],"category_scores_gemma":[0.0007430688,0.0001192946,0.00009591124,0.0001637406,0.0000845025,0.00003944114,0.0001179584,0.000190286,0.0001037071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008732029,"about_ca_system_score_gemma":0.000045118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000128285,"about_ca_topic_score_gemma":0.00000367223,"domain_scores_codex":[0.9988443,0.00005383476,0.0002732257,0.0004378552,0.00007620599,0.0003146036],"domain_scores_gemma":[0.9992912,0.000319164,0.00007453618,0.0001914731,0.00005421025,0.00006937159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004434746,0.0001151214,0.003951464,0.00001218856,0.00002757393,0.0000210034,0.00003055684,5.495217e-7,0.9901106,0.0003159287,0.0001103481,0.005260306],"study_design_scores_gemma":[0.0004108933,0.00001597129,0.0004800808,0.00001860063,0.00001513781,0.00001702364,0.00008339175,0.00009170264,0.9877272,0.001566031,0.009411975,0.0001619814],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9781367,0.0001550833,0.00001514984,0.0005164181,0.00007387393,0.00003145795,0.00002678274,0.00003600393,0.02100857],"genre_scores_gemma":[0.9982609,0.00006917763,0.0002317497,0.0007715982,0.0001689771,0.00001461592,0.00009823665,0.00000986785,0.0003748725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02063369,"threshold_uncertainty_score":0.9829627,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03365436732524065,"score_gpt":0.2907494307509164,"score_spread":0.2570950634256758,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}