{"id":"W3177875601","doi":"10.1007/s40121-021-00478-8","title":"COVID-19: Zinc and Angiotensin-Converting Enzyme 2 (ACE2) Deficiencies as Determinants of Risk and Severity of Disease: A Narrative Review","year":2021,"lang":"en","type":"review","venue":"Infectious Diseases and Therapy","topic":"Trace Elements in Health","field":"Nursing","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hillsborough Hospital","funders":"","keywords":"Angiotensin-converting enzyme 2; Medicine; Blood pressure; Control (management); Renin–angiotensin system; Virus; Cytokine storm; Coronavirus disease 2019 (COVID-19); Disease; Virology; Endocrinology; Internal medicine; Computer science; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001811731,0.0008425881,0.002244186,0.003194724,0.0003653447,0.002133781,0.00107471,0.001479705,0.005074244],"category_scores_gemma":[0.009030608,0.0003454369,0.002471293,0.003197753,0.0004743725,0.001651013,0.0008834153,0.001321587,0.000528258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00100921,"about_ca_system_score_gemma":0.003722794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003840015,"about_ca_topic_score_gemma":0.0058749,"domain_scores_codex":[0.9990562,0.0002502271,0.0003128406,0.0001546704,0.0001700106,0.00005618355],"domain_scores_gemma":[0.9948226,0.00380949,0.0007199024,0.00006132957,0.0005014406,0.00008528063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005431697,0.00007385349,0.00359055,0.3882534,0.003076345,0.000417002,0.0004874833,0.0003337951,0.0003989013,0.004428678,0.03288867,0.5655082],"study_design_scores_gemma":[0.0001482766,0.0003487623,0.01147772,0.5010689,0.01652601,0.003719189,0.000978066,0.0003291062,0.000403868,0.004614797,0.4602692,0.0001160515],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002073155,0.9988785,0.00004871293,0.000434102,0.0001048256,0.00001003333,0.00008587382,0.000002254322,0.0002283187],"genre_scores_gemma":[0.002411903,0.996726,0.0001146297,0.0003574826,0.0001635393,0.00002415824,0.0001001643,0.000001446669,0.0001005782],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005074244,"threshold_uncertainty_score":0.01697499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03393787584713626,"score_gpt":0.378229334760035,"score_spread":0.3442914589128987,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}