{"id":"W3178029032","doi":"10.1101/2021.07.08.451700","title":"Hepatoprotective effects of Aureobasidium pullulans derived Beta 1,3-1,6 biological response modifier glucans in a STAM- animal model of non-alcoholic steatohepatitis","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Steatohepatitis; Steatosis; Sirius Red; Fatty liver; Cirrhosis; Medicine; Fibrosis; Inflammation; Internal medicine; Gastroenterology; Pathology; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000526089,0.0007233671,0.001763231,0.0005055685,0.00005843304,0.00003974622,0.0003255463,0.0007600824,0.00002642105],"category_scores_gemma":[0.0004478679,0.0006774099,0.0005083519,0.0006090718,0.0002504635,0.00009836833,0.0004871836,0.000704502,0.000004369912],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006291674,"about_ca_system_score_gemma":0.002014776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008527421,"about_ca_topic_score_gemma":0.0000226735,"domain_scores_codex":[0.9961554,0.0005094346,0.0009022683,0.001240764,0.000579056,0.000613025],"domain_scores_gemma":[0.9966435,0.0002971057,0.0005572629,0.001347184,0.0007501084,0.0004047923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001747454,0.002058624,0.1965054,0.001507472,0.0007865349,0.0007365841,0.0001341719,0.0001723599,0.7962837,0.00005801537,0.000007444189,0.000002239886],"study_design_scores_gemma":[0.001900098,0.0004316446,0.5136488,0.001446452,0.000389489,3.663357e-8,0.00000999613,0.002333534,0.4795304,0.000001001906,0.000002179923,0.0003063467],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936328,0.001786632,0.0006003777,0.0001761588,0.0001794943,0.002747276,0.0007889246,0.00008463819,0.000003683846],"genre_scores_gemma":[0.9951813,0.0007909877,0.002653796,0.00009614329,0.00007154487,0.001096457,0.000003757517,0.0001044492,0.000001620786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3171434,"threshold_uncertainty_score":0.9995677,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02091827470058484,"score_gpt":0.2431185972117446,"score_spread":0.2222003225111598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}