{"id":"W3178278608","doi":"10.1038/s41392-021-00681-6","title":"Catch-as-catch-can: mRNA vaccination boosts immune responses to SARS-CoV-2 variants","year":2021,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences North","funders":"","keywords":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); 2019-20 coronavirus outbreak; Vaccination; Immune system; Biology; Virology; Sars virus; Messenger RNA; Immunology; Computational biology; Medicine; Genetics; Gene; Pathology; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006188374,0.0007212077,0.001002899,0.000938434,0.000312118,0.0001938808,0.0002984867,0.001093376,0.0006171372],"category_scores_gemma":[0.00008785625,0.0006665905,0.0004128148,0.001029822,0.0001089003,0.0001914919,0.00003275246,0.002194061,0.000129267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002484979,"about_ca_system_score_gemma":0.0009001831,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007434923,"about_ca_topic_score_gemma":0.00003245027,"domain_scores_codex":[0.995521,0.0005583452,0.0007348994,0.00119978,0.001148542,0.0008374021],"domain_scores_gemma":[0.9982101,0.0002145118,0.000173073,0.0007006479,0.0006087536,0.00009290625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003783874,0.0002511898,0.0002046514,0.0002662344,0.0006877389,0.0009679171,0.0016209,2.841084e-7,0.9175743,0.00002237373,0.05583943,0.01878108],"study_design_scores_gemma":[0.002561514,0.0007746671,0.001481752,0.0001604238,0.00008391232,0.0003084836,0.0001055288,0.00001162261,0.478901,0.0002874405,0.5148779,0.000445755],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.4833555,0.01084675,0.0006368228,0.4994384,0.001546721,0.002464586,0.0001804964,0.0003434186,0.001187256],"genre_scores_gemma":[0.136558,0.0009548079,0.0002020401,0.8572631,0.003083208,0.0002432622,0.0003608353,0.0002004104,0.001134381],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.4590384,"threshold_uncertainty_score":0.9995785,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05040670122201239,"score_gpt":0.3339923691617706,"score_spread":0.2835856679397582,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}