{"id":"W3178409740","doi":"10.3390/microorganisms9071483","title":"Potential Probiotic Bacillus subtilis Isolated from a Novel Niche Exhibits Broad Range Antibacterial Activity and Causes Virulence and Metabolic Dysregulation in Enterotoxic E. coli","year":2021,"lang":"en","type":"article","venue":"Microorganisms","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Guelph","funders":"Ontario Ministry of Agriculture, Food and Rural Affairs; Swine Innovation Porc","keywords":"Microbiology; Virulence; Bacillus subtilis; Biology; Staphylococcus aureus; Antimicrobial; Probiotic; Bacteria; Antibacterial activity; Salmonella; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001131016,0.0004532799,0.0003325609,0.000202145,0.0001386747,0.0003217968,0.0001326559,0.0002925505,0.0005522162],"category_scores_gemma":[0.0001862506,0.00008963958,0.0002028668,0.0002346192,0.0001437901,0.0001829283,0.0002818064,0.000445426,0.0001622631],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009830871,"about_ca_system_score_gemma":0.0001294718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004229103,"about_ca_topic_score_gemma":0.0006075088,"domain_scores_codex":[0.9998128,0.00003269999,0.00002232859,0.00004054614,0.00006267213,0.00002899159],"domain_scores_gemma":[0.9999038,0.00001009869,0.00003490318,0.000007378141,0.00001837031,0.00002541894],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009142426,0.00003213382,0.000948058,0.00005516279,0.000007089979,0.00008908066,0.00001305551,0.00001742957,0.9974233,0.00001019787,0.00002602023,0.001287081],"study_design_scores_gemma":[0.00001814633,0.001156996,0.05196279,0.00003543833,0.00007117344,0.001879365,0.0002571182,0.0006030728,0.9415419,0.00006342286,0.002396125,0.00001451861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967638,0.001364494,0.0009294572,0.000123132,0.00002289224,0.00001104156,0.0003595529,0.00002199073,0.0004035496],"genre_scores_gemma":[0.9951532,0.0009479696,0.00205748,0.0001095991,0.00001631545,0.00001900181,0.0009008186,0.00001165137,0.0007839422],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005522162,"threshold_uncertainty_score":0.001847327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01097478332301424,"score_gpt":0.1970477264181439,"score_spread":0.1860729430951296,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}