{"id":"W3178475819","doi":"","title":"Faricimab in Neovascular Age-Related Macular Degeneration: 1-Year Efficacy, Safety, and Durability in the Phase 3 TENAYA and LUCERNE Trials","year":2021,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Roche (Canada)","funders":"","keywords":"Macular degeneration; Medicine; Durability; Ophthalmology; Degeneration (medical); Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002371105,0.0001891777,0.0005428057,0.0001267654,0.0001896505,0.00006289483,0.0001222771,0.00009609245,0.00009389457],"category_scores_gemma":[0.002967795,0.0001232444,0.0000768641,0.001141034,0.002704188,0.0001505472,0.0001212099,0.0002278587,0.000005472671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001004462,"about_ca_system_score_gemma":0.0003566406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002038362,"about_ca_topic_score_gemma":0.000007683029,"domain_scores_codex":[0.9972056,0.000933986,0.0005124748,0.0006599271,0.000372044,0.0003160091],"domain_scores_gemma":[0.9989585,0.0004061635,0.0001139175,0.0002571462,0.0001138498,0.0001504572],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001116325,0.003318136,0.5717487,0.00008464874,0.0001789707,0.02084324,0.003725842,0.00005767541,0.3900066,0.00161015,0.000008078179,0.007301691],"study_design_scores_gemma":[0.007404718,0.0007557116,0.9662444,0.0000902705,0.0001280519,0.001317756,0.0004686808,0.0006109251,0.01906584,0.003733839,0.00003488304,0.0001449456],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945262,0.002167077,0.000001475766,0.001969848,0.00005078752,0.0007043542,0.000009230871,0.000009019516,0.0005619967],"genre_scores_gemma":[0.9992948,0.00008585156,0.000255277,0.0002298992,0.00001338655,0.00002861801,0.00003382462,0.000007209864,0.00005115824],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3944957,"threshold_uncertainty_score":0.9963694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06415740920361665,"score_gpt":0.3961264490210825,"score_spread":0.3319690398174658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}