{"id":"W3178620716","doi":"10.1158/1538-7445.am2021-2698","title":"Abstract 2698: Spatial gene expression profiling in breast cancer","year":2021,"lang":"en","type":"article","venue":"Cancer Research","topic":"Single-cell and spatial transcriptomics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Ontario Institute for Cancer Research","funders":"","keywords":"Breast cancer; Lumpectomy; Immune system; Transcriptome; Cancer research; Cancer; Medicine; Gene expression profiling; Pathology; Biology; Internal medicine; Immunology; Mastectomy; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001386112,0.0001456676,0.0001810089,0.0006053099,0.0001613781,0.0002691918,0.0001304497,0.000166792,0.001488597],"category_scores_gemma":[0.0001766685,0.000092803,0.0001544122,0.0008725447,0.0001269304,0.0001277912,0.0001606764,0.0001455271,0.0004639131],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000250605,"about_ca_system_score_gemma":0.0002369644,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001078819,"about_ca_topic_score_gemma":0.002086237,"domain_scores_codex":[0.9998481,0.00001511094,0.000008478816,0.00004444692,0.00006456365,0.00001921901],"domain_scores_gemma":[0.9999318,0.00001560427,0.00001520009,0.000006416034,0.00002506578,0.000005848599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001341178,0.00001614136,0.005683938,0.00007870045,0.00001266016,0.00003571936,0.0000278642,0.0008109473,0.9800625,0.0001121279,0.0002523131,0.01277302],"study_design_scores_gemma":[0.00001248694,0.0002627667,0.1784858,0.00001324936,0.00005697173,0.0006644542,0.0001879971,0.02455452,0.7865002,0.000419495,0.008821296,0.00002076356],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.9585797,0.001344383,0.03088134,0.0001169493,0.000032346,0.00005694179,0.005584252,0.0004762902,0.002927731],"genre_scores_gemma":[0.9478123,0.0006726859,0.04121514,0.00007769872,0.00001856986,0.0001216453,0.005905834,0.00007711142,0.004099083],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.001488597,"threshold_uncertainty_score":0.004979849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05469841785174891,"score_gpt":0.3624981364654367,"score_spread":0.3077997186136878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}