{"id":"W3178890732","doi":"10.3390/cells10071794","title":"Implant Fibrosis and the Underappreciated Role of Myofibroblasts in the Foreign Body Reaction","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Mitacs; Canada Foundation for Innovation; Ontario Research Foundation","keywords":"Myofibroblast; Implant; Fibrosis; Foreign body; Medicine; Wound healing; Pathology; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00155956,0.0004422008,0.0009364688,0.002071264,0.0004149521,0.00197769,0.0005082471,0.00221041,0.001860947],"category_scores_gemma":[0.001855354,0.0002421359,0.000746232,0.001223826,0.002233011,0.003283669,0.000857953,0.0018249,0.0004891327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000564809,"about_ca_system_score_gemma":0.0009801063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000832453,"about_ca_topic_score_gemma":0.000807407,"domain_scores_codex":[0.9992115,0.0001824376,0.0001311995,0.0001200198,0.0002675441,0.00008730033],"domain_scores_gemma":[0.9981755,0.000981541,0.0004047833,0.00005407632,0.0003133462,0.00007071598],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006018019,0.0001442016,0.006541313,0.04607385,0.0003021936,0.007350286,0.002696256,0.0008163099,0.03261213,0.05273706,0.01795159,0.832173],"study_design_scores_gemma":[0.00004839307,0.0008408505,0.02119571,0.02134833,0.0006364993,0.04642092,0.003792073,0.0007966341,0.01789108,0.05034923,0.836494,0.0001863078],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001383704,0.9955776,0.0003742629,0.001609335,0.0004440952,0.000002588344,0.000006560848,0.000004270826,0.0005975809],"genre_scores_gemma":[0.02143842,0.9730482,0.0005529209,0.00158208,0.002339883,0.000008456417,0.00001617237,0.000004478112,0.001009391],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00221041,"threshold_uncertainty_score":0.008247793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01253200202703592,"score_gpt":0.2626553746024359,"score_spread":0.2501233725754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}