{"id":"W3178890732","doi":"10.3390/cells10071794","title":"Implant Fibrosis and the Underappreciated Role of Myofibroblasts in the Foreign Body Reaction","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Mitacs; Canada Foundation for Innovation; Ontario Research Foundation","keywords":"Myofibroblast; Implant; Fibrosis; Foreign body; Medicine; Wound healing; Pathology; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002612328,0.0001635222,0.0004188493,0.00003888389,0.00004834274,0.00003021658,0.0001720295,0.0001976227,0.00001010145],"category_scores_gemma":[0.00002253484,0.00009208247,0.0002545647,0.0001161693,0.00004077894,0.000002040607,0.00008669205,0.0001754347,0.000002256051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001117802,"about_ca_system_score_gemma":0.00006889163,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004979019,"about_ca_topic_score_gemma":0.00002369963,"domain_scores_codex":[0.9990233,0.0002454284,0.000296863,0.0002314274,0.0000791707,0.0001237787],"domain_scores_gemma":[0.9993073,0.0000866518,0.0001961165,0.0003577208,0.0000334244,0.000018762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001231306,0.0002987413,0.000001244519,0.003228707,0.000789206,0.00001216739,0.0003144651,0.000005651009,0.4933058,0.00844629,0.008502816,0.4849718],"study_design_scores_gemma":[0.0002061426,0.00006289165,7.220526e-7,0.0007971554,0.0001636508,0.00007814762,0.0002063299,0.0000268592,0.01424916,0.0001407973,0.9839585,0.0001096007],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004372706,0.9974569,0.000047338,0.00001289077,0.0001145859,0.0003912378,0.00004495934,0.000001895897,0.001492898],"genre_scores_gemma":[0.004925103,0.99425,0.0000167498,0.00002960304,0.00008201305,0.00004872618,0.0004353776,0.00001815411,0.0001942479],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9754557,"threshold_uncertainty_score":0.3755014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01253200202703592,"score_gpt":0.2626553746024359,"score_spread":0.2501233725754,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}