{"id":"W3179119699","doi":"10.1016/j.fertnstert.2021.06.016","title":"Quantitative selection of single human sperm with high DNA integrity for intracytoplasmic sperm injection","year":2021,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; CReATe Fertility Centre; Hospital for Sick Children; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Ontario; University of Toronto; Canada Excellence Research Chairs, Government of Canada; Ontario Research Foundation","keywords":"Intracytoplasmic sperm injection; Andrology; Sperm; Selection (genetic algorithm); Biology; Embryo; Medicine; Cell biology; In vitro fertilisation; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009236376,0.0004506213,0.0004196441,0.0006083093,0.0002558959,0.0003912971,0.0004182993,0.0005455868,0.002803323],"category_scores_gemma":[0.0007499802,0.0003602686,0.0002689909,0.0004227103,0.0004184756,0.0002117894,0.0003013898,0.0006608916,0.0006074663],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002437647,"about_ca_system_score_gemma":0.0003112125,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005482717,"about_ca_topic_score_gemma":0.001112529,"domain_scores_codex":[0.9992951,0.0002037399,0.00005730527,0.0001772071,0.0001775252,0.0000890646],"domain_scores_gemma":[0.9991745,0.0003603464,0.0001154382,0.0001206923,0.0001421663,0.0000867061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004437876,0.00001581919,0.00011364,0.000009597371,0.000002662444,0.000004915564,0.000009096162,0.00002958127,0.9987139,0.00005039046,0.0000222725,0.000983819],"study_design_scores_gemma":[0.00001186962,0.0001730133,0.00168604,0.000002012346,0.00001375168,0.00005477032,0.000006081588,0.0008719224,0.9965364,0.00001794055,0.0006225949,0.000003594614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8959072,0.00155351,0.09593369,0.0002639616,0.00008610251,0.0006838577,0.001057529,0.000851617,0.003662515],"genre_scores_gemma":[0.9254743,0.0006879481,0.0632912,0.0001968263,0.00003416133,0.0004172883,0.002228139,0.0003038741,0.007366268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002803323,"threshold_uncertainty_score":0.009378076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04294270908165638,"score_gpt":0.2902010592885343,"score_spread":0.247258350206878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}