{"id":"W3179219075","doi":"10.1371/journal.ppat.1009661","title":"Respiring to infect: Emerging links between mitochondria, the electron transport chain, and fungal pathogenesis","year":2021,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Institute of Infection and Immunity; Canadian Institutes of Health Research; National Research Foundation of Korea; Ministry of Science, ICT and Future Planning; National Research Foundation; Canadian Institute for Advanced Research; Burroughs Wellcome Fund","keywords":"Cryptococcus neoformans; Aspergillus fumigatus; Biology; Candida albicans; Microbiology; Antifungal drug; Cryptococcosis; Virulence; Aspergillosis; Disease; Fungus; Population; Mitochondrion; Immunology; Medicine; Gene; Pathology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006180315,0.0006971729,0.000851622,0.0008910295,0.000564293,0.002105608,0.0006415237,0.001954114,0.005175351],"category_scores_gemma":[0.0006968716,0.0001526486,0.0003865932,0.0009560516,0.0008871364,0.003041403,0.001088454,0.002475081,0.0009001045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007906014,"about_ca_system_score_gemma":0.0008638321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000651788,"about_ca_topic_score_gemma":0.001088702,"domain_scores_codex":[0.999752,0.00004943951,0.00002307405,0.00006633806,0.00006162759,0.00004752647],"domain_scores_gemma":[0.9994394,0.0002195869,0.0001147108,0.00001335803,0.0001185784,0.00009429206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005883306,0.0001722703,0.00530718,0.02338312,0.0002421231,0.003244562,0.001139248,0.0006958302,0.05257811,0.06345414,0.0729356,0.7762597],"study_design_scores_gemma":[0.00003342149,0.000533119,0.01352715,0.005979188,0.0002521243,0.009936596,0.00145317,0.000778431,0.006776164,0.05179974,0.9088353,0.00009563101],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001539247,0.9902825,0.0009942573,0.004568588,0.0008833006,0.000005626261,0.00006394243,0.00002257867,0.001639932],"genre_scores_gemma":[0.01396296,0.9790295,0.000905079,0.001788278,0.003000485,0.00001108537,0.0001282371,0.000006735771,0.001167609],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005175351,"threshold_uncertainty_score":0.0173133,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0543793410253259,"score_gpt":0.3385580104094412,"score_spread":0.2841786693841153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}