{"id":"W3179738138","doi":"10.1136/bmjopen-2020-041490","title":"Eliminating hepatitis C in a rural Appalachian county: protocol for the Kentucky Viral Hepatitis Treatment Study (KeY Treat), a phase IV, single-arm, open-label trial of sofosbuvir/velpatasvir for the treatment of hepatitis C","year":2021,"lang":"en","type":"article","venue":"BMJ Open","topic":"Hepatitis C virus research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Population and Public Health","funders":"National Center for Advancing Translational Sciences; National Institute on Drug Abuse; National Institutes of Health","keywords":"Medicine; Sofosbuvir; Hepatitis C; Open label; Randomized controlled trial; Internal medicine; Chronic hepatitis; Virology; Ribavirin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01803312,0.003196873,0.004088714,0.001440171,0.004813541,0.002926807,0.002640497,0.003635461,0.04290404],"category_scores_gemma":[0.009475235,0.0018847,0.002409772,0.002063052,0.002123616,0.002340138,0.001736981,0.004612785,0.01099171],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005480938,"about_ca_system_score_gemma":0.02045759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007594516,"about_ca_topic_score_gemma":0.02042422,"domain_scores_codex":[0.9901247,0.005836133,0.0009801093,0.001125002,0.00076487,0.001169123],"domain_scores_gemma":[0.9932503,0.0006727992,0.001203275,0.0006763878,0.002713992,0.001483422],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5933847,0.05959344,0.01700231,0.02339799,0.001341805,0.001936844,0.004215602,0.004396014,0.01302621,0.009918637,0.16916,0.1026265],"study_design_scores_gemma":[0.4792682,0.06651889,0.06711281,0.007891282,0.0009986538,0.0005933217,0.001954711,0.003311578,0.00426226,0.005639444,0.3620602,0.0003887143],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.004566988,0.0002423778,0.001204716,0.0002625707,0.0001838042,0.9880476,0.003310736,0.00005960424,0.002121623],"genre_scores_gemma":[0.004764655,0.0002083887,0.002427462,0.0003435709,0.00004618548,0.9900159,0.001136518,0.00000901083,0.001048244],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.04290404,"threshold_uncertainty_score":0.1435283,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2432169303719519,"score_gpt":0.5089549126681229,"score_spread":0.265737982296171,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}