{"id":"W3179798052","doi":"","title":"Modified Exosomes for Extended Intravitreal Drug Delivery","year":2021,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"","keywords":"Microvesicles; Drug delivery; Drug; Medicine; Pharmacology; Ophthalmology; Chemistry; microRNA; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002468207,0.0002442747,0.0001955566,0.0001168431,0.0001420607,0.0005091446,0.0001719371,0.0005305308,0.0006433566],"category_scores_gemma":[0.000255012,0.0001012187,0.0002843807,0.00008247632,0.0001301602,0.0004740698,0.000460753,0.0004737139,0.0002498309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002979167,"about_ca_system_score_gemma":0.0002474237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003067603,"about_ca_topic_score_gemma":0.0004208337,"domain_scores_codex":[0.9998573,0.00002149521,0.00001254148,0.00002866057,0.00004418412,0.00003577641],"domain_scores_gemma":[0.9999181,0.00001890703,0.00002073166,0.00001175746,0.00001540947,0.00001514383],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001504364,0.00005672167,0.0001580021,0.00009488391,0.00002311884,0.0001568053,0.00004823814,0.0003176545,0.9844149,0.0009566705,0.0003420429,0.0132805],"study_design_scores_gemma":[0.00003208439,0.0002334417,0.0005958006,0.00001500652,0.00002977469,0.0002089951,0.00001846848,0.001510841,0.9886073,0.0001458846,0.008587227,0.00001517823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9514251,0.01211026,0.03137868,0.0004162557,0.0004693782,0.0001860162,0.0004201368,0.0002705616,0.00332366],"genre_scores_gemma":[0.9805812,0.00258755,0.0117281,0.0001546135,0.00003887424,0.0001123258,0.0001965124,0.00004653863,0.004554247],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006433566,"threshold_uncertainty_score":0.002161562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02672977454549123,"score_gpt":0.3230196084951514,"score_spread":0.2962898339496601,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}