{"id":"W318007764","doi":"10.1182/blood.v122.21.2501.2501","title":"Identification and Characterization By ChIP-Seq Of Genomic Sites Bound By E2A-PBX1 In Acute Lymphoblastic Leukemia Demonstrates Associations With p300 Recruitment, Transcriptionally Active Chromatin and Abundant Transcription","year":2013,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chromatin immunoprecipitation; Chromatin; CTCF; Biology; ChIP-sequencing; Molecular biology; Transcription factor; RNA polymerase II; Promoter; Transcription (linguistics); Gene; H3K4me3; Enhancer; Genetics; ChIP-on-chip; Gene expression; Chromatin remodeling","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001242486,0.0002133303,0.0003251329,0.0003816883,0.000193117,0.0003247113,0.0002126155,0.0001955415,0.001323647],"category_scores_gemma":[0.0001504786,0.0001703176,0.0002540818,0.0004282497,0.0001789322,0.0000875166,0.000193524,0.0002521648,0.0005653902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001760008,"about_ca_system_score_gemma":0.0001484198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001790009,"about_ca_topic_score_gemma":0.003461579,"domain_scores_codex":[0.9998674,0.000007334797,0.000005032467,0.0000578196,0.00003304131,0.00002939899],"domain_scores_gemma":[0.9998876,0.00003407478,0.00002150759,0.00001157312,0.00002021531,0.00002498501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000121076,0.00001315328,0.005242647,0.00004284186,0.00001364932,0.00004615456,0.00003636906,0.000270223,0.9925796,0.00003984377,0.0001089154,0.001485595],"study_design_scores_gemma":[0.00003033824,0.0001575475,0.4326953,0.0000130524,0.00006499261,0.0004791493,0.0002207216,0.00925961,0.5522416,0.0001502665,0.004669128,0.00001840448],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844482,0.000537447,0.006972013,0.00004073617,0.00001106874,0.00002413179,0.007264027,0.0001460843,0.0005564153],"genre_scores_gemma":[0.9744347,0.0003818214,0.009528399,0.0001007866,0.00000978107,0.00007025171,0.01337352,0.00008271306,0.002018084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001790009,"threshold_uncertainty_score":0.004428029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433593922455737,"score_gpt":0.2474288338219285,"score_spread":0.2330928945973711,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}