{"id":"W3180370965","doi":"10.1038/s41467-021-24038-3","title":"Renewable fatty acid ester production in Clostridium","year":2021,"lang":"en","type":"article","venue":"Nature Communications","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Energy Efficiency; Alabama Agricultural Experiment Station; National Institute of Food and Agriculture; University of Illinois at Urbana-Champaign; U.S. Department of Agriculture; Auburn University; University of Waterloo; Aberystwyth University; Office of Energy Efficiency and Renewable Energy; U.S. Department of Energy","keywords":"Bioproduction; Metabolic engineering; Clostridia; Bioprocess; Biochemical engineering; Metabolic pathway; Bioprocess engineering; Biotechnology; Chemistry; Biochemistry; Biology; Enzyme; Bacteria; Engineering","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001731968,0.0006597709,0.0001534166,0.0003696987,0.0002745065,0.000372556,0.000275413,0.0002884681,0.0004530596],"category_scores_gemma":[0.0001968148,0.0001309077,0.000290746,0.0005955867,0.0001146658,0.0002626041,0.000471881,0.0004448192,0.0003351005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005128346,"about_ca_system_score_gemma":0.0007012636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004397605,"about_ca_topic_score_gemma":0.004518445,"domain_scores_codex":[0.9997576,0.00002414586,0.00002194601,0.00003533248,0.00008675909,0.00007423136],"domain_scores_gemma":[0.9999156,0.000008469996,0.00001694902,0.00001092734,0.0000233204,0.00002473282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005920783,0.00005170858,0.0006226461,0.00007319515,0.000004093394,0.0001210482,0.00001575503,0.0002427479,0.9951324,0.0001707929,0.00006148824,0.003444803],"study_design_scores_gemma":[0.00001876128,0.0004014933,0.006642543,0.00001883389,0.00002436026,0.0003100364,0.0001098108,0.001861422,0.9869438,0.0001189781,0.00353338,0.00001665248],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924481,0.0005925784,0.003099096,0.0001756188,0.00004716252,0.00003769976,0.0007489579,0.00007119718,0.002779598],"genre_scores_gemma":[0.9851752,0.0007682564,0.007324003,0.00007437612,0.000007307439,0.00003285108,0.002335565,0.00004492352,0.004237512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004397605,"threshold_uncertainty_score":0.008744001,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01072818587044756,"score_gpt":0.2607193912726174,"score_spread":0.2499912054021698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}