{"id":"W3180597578","doi":"10.1371/journal.pgen.1009459","title":"NuA4 and SAGA acetyltransferase complexes cooperate for repair of DNA breaks by homologous recombination","year":2021,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canada Research Chairs; Canadian Institutes of Health Research; Fondation CHU de Québec; Université Laval","keywords":"Biology; RAD51; Homologous recombination; Chromatin; DNA repair; Histone; Cell biology; Genetics; Acetyltransferase; DNA; Acetylation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003077856,0.000462996,0.0003458899,0.0004058201,0.0002642268,0.0005516893,0.0003819285,0.0003864895,0.0009588115],"category_scores_gemma":[0.0001900158,0.0003724732,0.0002848426,0.0001742631,0.0002292932,0.0003676696,0.0007457017,0.0003489194,0.000497714],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003783996,"about_ca_system_score_gemma":0.0002298106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003165851,"about_ca_topic_score_gemma":0.0006476167,"domain_scores_codex":[0.9997119,0.00005199768,0.00002228581,0.00006953588,0.00008446362,0.00005970143],"domain_scores_gemma":[0.9998201,0.00001638752,0.00005013717,0.00003295836,0.00001797046,0.00006240397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007039138,0.00001248178,0.000806573,0.00001908202,0.00001004514,0.00006333458,0.000009005285,0.0001059032,0.9972419,0.0002522267,0.00002211651,0.001387012],"study_design_scores_gemma":[0.00001099515,0.000165356,0.01791259,0.000004475372,0.00002358665,0.0009093666,0.00004067405,0.002774486,0.9741504,0.0003788576,0.003619136,0.00001005109],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867164,0.003171344,0.008011821,0.0001029251,0.00002676517,0.00001551256,0.0001091633,0.0001800928,0.001665882],"genre_scores_gemma":[0.9915841,0.0004413094,0.004845712,0.0000186719,0.000005984374,0.000008609949,0.0002138215,0.00002515182,0.002856562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009588115,"threshold_uncertainty_score":0.003207505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0144952018345082,"score_gpt":0.2354358835902056,"score_spread":0.2209406817556974,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}