{"id":"W3180625801","doi":"10.1002/hep4.1767","title":"Analysis of HBsAg Immunocomplexes and cccDNA Activity During and Persisting After NAP‐Based Therapy","year":2021,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"","keywords":"HBsAg; cccDNA; Medicine; Seroconversion; Hepatitis B virus; Antibody; Virology; Hepatitis B; Immunology; Internal medicine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008670192,0.0003527288,0.0004130774,0.0008490317,0.0002508003,0.0004764582,0.0001897243,0.0003666037,0.0008356603],"category_scores_gemma":[0.001577491,0.0002146195,0.0002834871,0.0004968608,0.0002144221,0.000249377,0.0001854298,0.0004555814,0.000223132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000189057,"about_ca_system_score_gemma":0.0001289541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008622918,"about_ca_topic_score_gemma":0.0007256762,"domain_scores_codex":[0.9995828,0.0001036357,0.00003590274,0.00007636087,0.0001215736,0.00007979124],"domain_scores_gemma":[0.9988802,0.0002043581,0.0002898161,0.00008560511,0.0003017657,0.0002382926],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.009472218,0.0005637968,0.6065444,0.0002123877,0.0001682515,0.001032768,0.001879777,0.0002599842,0.3528488,0.0001157138,0.0001602974,0.02674154],"study_design_scores_gemma":[0.00003862504,0.003636841,0.9474565,0.00001397281,0.0001426121,0.0007205438,0.0003614967,0.0006292812,0.04604261,0.00003858623,0.0009006493,0.00001823738],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980862,0.0006575311,0.0003280122,0.000007752265,0.000005600803,0.00003781405,0.0001612734,0.00001116271,0.0007047182],"genre_scores_gemma":[0.9985288,0.000132946,0.0002014986,0.00001808689,0.00000884765,0.00004763475,0.0003223941,0.000005069225,0.0007347019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008670192,"threshold_uncertainty_score":0.004585326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05518669292352572,"score_gpt":0.3288003217256096,"score_spread":0.2736136288020838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}