{"id":"W3180625801","doi":"10.1002/hep4.1767","title":"Analysis of HBsAg Immunocomplexes and cccDNA Activity During and Persisting After NAP‐Based Therapy","year":2021,"lang":"en","type":"article","venue":"Hepatology Communications","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada)","funders":"","keywords":"HBsAg; cccDNA; Medicine; Seroconversion; Hepatitis B virus; Antibody; Virology; Hepatitis B; Immunology; Internal medicine; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001307445,0.0001021106,0.0004607383,0.0001893445,0.0002604124,0.000008941792,0.00009523198,0.00005489132,0.00006840864],"category_scores_gemma":[0.0001177092,0.0001015577,0.00009206759,0.0004321781,0.0004534345,0.00004358468,0.0002703346,0.0001668371,9.974202e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003169653,"about_ca_system_score_gemma":0.0000712945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009568794,"about_ca_topic_score_gemma":0.004946066,"domain_scores_codex":[0.9992073,0.000194977,0.0002075542,0.0001808361,0.00007173104,0.0001376003],"domain_scores_gemma":[0.9984021,0.0003288093,0.00009102144,0.0009695526,0.0001628117,0.00004575469],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00004459868,0.0001476588,0.9821384,0.00003700996,0.0008731547,0.00001119887,0.0006074015,5.751506e-7,0.01433365,0.00009809028,0.000005775928,0.001702512],"study_design_scores_gemma":[0.0005977911,0.00003108282,0.992312,0.00004232759,0.0006094989,0.00003487895,0.0001150625,0.002974359,0.002889177,0.00001929744,0.0002946986,0.00007985894],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838709,0.01063573,0.00005160822,0.004624235,0.0000083928,0.0001164084,0.00002415445,0.00002716494,0.0006414559],"genre_scores_gemma":[0.9912235,0.004768361,0.003635667,0.0002452467,0.000004198565,0.00005353863,0.00002817848,0.000009470036,0.00003179755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01144448,"threshold_uncertainty_score":0.4141404,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05518669292352572,"score_gpt":0.3288003217256096,"score_spread":0.2736136288020838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}