{"id":"W3180735302","doi":"10.2215/cjn.00920121","title":"Gene Expression Profiling in Kidney Transplants with Immune Checkpoint Inhibitor–Associated Adverse Events","year":2021,"lang":"en","type":"article","venue":"Clinical Journal of the American Society of Nephrology","topic":"Nephrotoxicity and Medicinal Plants","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Diabetes and Digestive and Kidney Diseases","keywords":"Medicine; Immune checkpoint; Immune system; Cancer research; Immunology; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001443632,0.0001718061,0.001214335,0.00004665514,0.00005258079,0.000001437393,0.0002390643,0.0001712772,0.00002455593],"category_scores_gemma":[0.0005085736,0.0001065666,0.0007644655,0.0004467049,0.0006784796,0.0000668042,0.0000774209,0.001163116,0.000001813344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008043784,"about_ca_system_score_gemma":0.0008737994,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000248492,"about_ca_topic_score_gemma":0.000006969206,"domain_scores_codex":[0.9970807,0.0005143479,0.001375625,0.0002206903,0.0004889067,0.000319723],"domain_scores_gemma":[0.9971276,0.0003720664,0.001634189,0.0002857611,0.0003034384,0.0002769689],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004498052,0.001245966,0.1977722,0.00009946272,0.0005467429,0.0002882919,0.0004229294,0.00002477549,0.7925451,6.420926e-7,0.00182806,0.0007278066],"study_design_scores_gemma":[0.0156046,0.003951787,0.5884895,0.003422086,0.000622426,0.001848606,0.002605655,0.00009497441,0.3817824,0.00009284954,0.001273724,0.0002113628],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922712,0.0001659582,0.0001447547,0.006913437,0.0002266828,0.0002301571,0.00001613378,0.000006849576,0.00002481577],"genre_scores_gemma":[0.971117,0.001061888,0.008007743,0.01944171,0.0002691253,0.000002744594,0.00001027014,0.00001885006,0.00007068341],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4107627,"threshold_uncertainty_score":0.5053226,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03095670479216775,"score_gpt":0.3274087104411055,"score_spread":0.2964520056489378,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}