{"id":"W3180831063","doi":"10.1007/s00011-021-01484-9","title":"The pathophysiology of immunoporosis: innovative therapeutic targets","year":2021,"lang":"en","type":"review","venue":"Inflammation Research","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Hôpital du Sacré-Cœur de Montréal","funders":"","keywords":"Osteoimmunology; Osteoclast; Osteoporosis; Medicine; Osteoblast; RANKL; Bone resorption; Bone remodeling; Osteolysis; Immunology; Bioinformatics; Internal medicine; Biology; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001114988,0.0001878521,0.0005543553,0.0001105168,0.0002118412,0.00004643293,0.0004449959,0.0002804522,0.00003904347],"category_scores_gemma":[0.0006986999,0.0001202513,0.0002314523,0.0006164027,0.0003568069,0.000003336696,0.000328982,0.0003101299,0.00002251057],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001507174,"about_ca_system_score_gemma":0.0009517183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007017022,"about_ca_topic_score_gemma":0.000004400211,"domain_scores_codex":[0.9972213,0.001270865,0.0005492258,0.0003145689,0.000337785,0.0003062873],"domain_scores_gemma":[0.9976022,0.0002228298,0.0002624779,0.0006923822,0.001179241,0.00004084766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001880379,0.00002575996,0.000001369837,0.001065587,0.0001894476,0.0000020957,0.0000249352,5.489183e-7,0.004754245,0.002329229,0.001595945,0.989992],"study_design_scores_gemma":[0.0000967172,0.00006156226,0.00002199929,0.0004653634,0.00004181236,0.000001848355,0.00008013386,5.868823e-7,0.002179121,0.000323744,0.9966107,0.0001164299],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001203464,0.9985756,0.0000260637,0.00004150428,0.0001353073,0.0004819646,0.00004250796,0.000004538231,0.0005722251],"genre_scores_gemma":[0.000192139,0.9974726,0.00002884156,0.00001226364,0.0003086758,0.0002984061,0.0007917894,0.0000270313,0.0008681992],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9950147,"threshold_uncertainty_score":0.4903706,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07206747132005485,"score_gpt":0.4163198791946772,"score_spread":0.3442524078746223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}