{"id":"W3181270705","doi":"10.1038/s41379-021-00865-z","title":"Interobserver variability in the assessment of stromal tumor-infiltrating lymphocytes (sTILs) in triple-negative invasive breast carcinoma influences the association with pathological complete response: the IVITA study","year":2021,"lang":"en","type":"article","venue":"Modern Pathology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":61,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Health Science Centre","funders":"Cliniques Universitaires Saint-Luc; U.S. Department of Health and Human Services; National Cancer Institute; Fondation contre le Cancer; Stichting Tegen Kanker; Fondation Saint Luc","keywords":"Medicine; Biopsy; Pathological; Breast cancer; Pathology; Intraclass correlation; Renal cell carcinoma; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.009138232,0.0004949077,0.0005766859,0.001207684,0.0003325218,0.001159377,0.0005303965,0.0007268909,0.0008586964],"category_scores_gemma":[0.0175592,0.0002958412,0.0006058164,0.0006816468,0.0005397548,0.0006667738,0.0008501784,0.0006619053,0.0002996732],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000287588,"about_ca_system_score_gemma":0.0002239327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008672742,"about_ca_topic_score_gemma":0.001227429,"domain_scores_codex":[0.994991,0.00260082,0.0004582548,0.000896716,0.0007925518,0.0002606509],"domain_scores_gemma":[0.9762734,0.01421523,0.003944147,0.003371282,0.00167134,0.0005245892],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00145856,0.0000244996,0.9865134,0.0000346607,0.0003589133,0.0000537689,0.0003582802,0.0003698,0.003036563,0.00004934709,0.0001201454,0.007621944],"study_design_scores_gemma":[0.00001572947,0.0003466137,0.9929695,0.00001889065,0.0002860494,0.0004082667,0.0002972374,0.002732423,0.002075661,0.0001528469,0.0006775302,0.00001923637],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954985,0.001379833,0.001572836,0.0000397886,0.00003510749,0.00001392593,0.0001133113,0.00002258954,0.001324094],"genre_scores_gemma":[0.9994727,0.00005291626,0.0001812037,0.00001230076,0.00002248743,0.000007585091,0.00008121556,0.00001259684,0.0001570194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9908618,"threshold_uncertainty_score":0.04832816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03240910133872378,"score_gpt":0.3029422878647602,"score_spread":0.2705331865260364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}