{"id":"W3181273552","doi":"10.1093/gbe/evab157","title":"A Eukaryote-Wide Perspective on the Diversity and Evolution of the ARF GTPase Protein Family","year":2021,"lang":"en","type":"article","venue":"Genome Biology and Evolution","topic":"Genomics and Phylogenetic Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of General Medical Sciences; National Institute of Environmental Health Sciences; Natural Environment Research Council; Sight Research UK","keywords":"Biology; Eukaryote; Evolutionary biology; Lineage (genetic); Protein family; Phylogenetics; Phylogenetic tree; Gene family; Genome; Bilateria; Three-domain system; Genetics; Evolution of mammals; Computational biology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001512863,0.0000969274,0.00009896508,0.00001350679,0.0005659014,0.000003666862,0.00008920689,0.0001099757,0.000002098538],"category_scores_gemma":[0.0001171591,0.00006267872,0.00005036608,0.0000670977,0.00030799,8.03401e-7,0.0005700835,0.00007443767,9.89123e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004349263,"about_ca_system_score_gemma":0.00005468091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001824643,"about_ca_topic_score_gemma":0.00007687508,"domain_scores_codex":[0.9993386,0.000137558,0.00009237592,0.000257674,0.00004078976,0.0001329555],"domain_scores_gemma":[0.9995791,0.00002196566,0.000063586,0.0002016855,0.0001096916,0.00002401271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00008355791,0.00003041219,0.158415,0.000007491667,0.00008479114,4.041487e-7,0.0002853576,0.00001226442,0.8251659,0.01578968,0.00005350657,0.0000715317],"study_design_scores_gemma":[0.0002494772,0.0002094474,0.9789171,0.000006796356,0.00002693354,0.000005533753,0.001137708,0.00001111276,0.008839965,0.009605001,0.0009019284,0.00008902403],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9871086,0.01098993,0.0002572244,0.0008948706,0.00008414918,0.0001935574,0.00004080853,0.000001677164,0.0004291053],"genre_scores_gemma":[0.999201,0.0003590169,0.00004411046,0.0001625967,0.00006912188,0.00001086036,0.000006052383,0.000003861908,0.0001433664],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.820502,"threshold_uncertainty_score":0.4352513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01041147247191202,"score_gpt":0.207333670586543,"score_spread":0.196922198114631,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}