{"id":"W3181291734","doi":"10.1016/j.jcin.2021.04.043","title":"Impact of Age on the Safety and Efficacy of Ticagrelor Monotherapy in Patients Undergoing PCI","year":2021,"lang":"en","type":"article","venue":"JACC: Cardiovascular Interventions","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences","funders":"Abbott Vascular; St. Jude Medical; Eisai; Janssen Scientific Affairs; Idorsia Pharmaceuticals; OrbusNeich; Siemens Medical Solutions USA; Daiichi-Sankyo; Medicines Company; Boston Scientific Corporation; Novartis Pharmaceuticals Corporation; Gilead Sciences; Bayer; Abbott Laboratories; CSL Behring; Chiesi Farmaceutici; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Edwards Lifesciences; Scott R. MacKenzie Foundation; Boehringer Ingelheim; Amgen; Regeneron Pharmaceuticals; Medtronic","keywords":"Ticagrelor; Medicine; Conventional PCI; Percutaneous coronary intervention; Aspirin; Hazard ratio; Internal medicine; Myocardial infarction; Clinical endpoint; Stroke (engine); Confidence interval; Cardiology; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005054595,0.0001635049,0.000707303,0.0001275282,0.00005421485,0.00001331243,0.00009037955,0.00007665014,0.0001852886],"category_scores_gemma":[0.0003026642,0.0001155865,0.005030091,0.0003360039,0.0001141072,0.00005080156,0.00005093428,0.0001647231,0.000005058422],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006997462,"about_ca_system_score_gemma":0.00009237339,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004401865,"about_ca_topic_score_gemma":0.00001156784,"domain_scores_codex":[0.9983431,0.0003424227,0.0004772303,0.0002639368,0.0003992446,0.0001740596],"domain_scores_gemma":[0.9987242,0.0001988735,0.00009225326,0.0007585387,0.0001563373,0.00006977464],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005778919,0.007884426,0.5652024,0.001774751,0.09196041,0.0005393564,0.001369343,0.005576867,0.0007009038,0.003546831,0.0004826197,0.3151831],"study_design_scores_gemma":[0.009901316,0.0005982532,0.9855213,0.00121906,0.0009981492,0.00002994361,0.000143342,0.00001952219,0.0007748826,0.00008235334,0.0005851779,0.0001267326],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866408,0.01092025,0.001041593,0.00006510656,0.00006286002,0.0004598837,0.00003342665,0.00001435711,0.000761767],"genre_scores_gemma":[0.9976044,0.002091712,0.00007740453,0.00003404255,0.00003158949,0.00001160059,0.00004795855,0.00002478685,0.00007651133],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4203188,"threshold_uncertainty_score":0.5072982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433357033887436,"score_gpt":0.2934884938865033,"score_spread":0.269154923547629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}