{"id":"W3181291734","doi":"10.1016/j.jcin.2021.04.043","title":"Impact of Age on the Safety and Efficacy of Ticagrelor Monotherapy in Patients Undergoing PCI","year":2021,"lang":"en","type":"article","venue":"JACC: Cardiovascular Interventions","topic":"Antiplatelet Therapy and Cardiovascular Diseases","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hamilton Health Sciences","funders":"Abbott Vascular; St. Jude Medical; Eisai; Janssen Scientific Affairs; Idorsia Pharmaceuticals; OrbusNeich; Siemens Medical Solutions USA; Daiichi-Sankyo; Medicines Company; Boston Scientific Corporation; Novartis Pharmaceuticals Corporation; Gilead Sciences; Bayer; Abbott Laboratories; CSL Behring; Chiesi Farmaceutici; Bristol-Myers Squibb; Eli Lilly and Company; AstraZeneca; Edwards Lifesciences; Scott R. MacKenzie Foundation; Boehringer Ingelheim; Amgen; Regeneron Pharmaceuticals; Medtronic","keywords":"Ticagrelor; Medicine; Conventional PCI; Percutaneous coronary intervention; Aspirin; Hazard ratio; Internal medicine; Myocardial infarction; Clinical endpoint; Stroke (engine); Confidence interval; Cardiology; Randomized controlled trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001109634,0.000222703,0.001084135,0.0003464245,0.0003028296,0.0012528,0.0002328426,0.0008287182,0.0018478],"category_scores_gemma":[0.008041962,0.0001778399,0.001422942,0.0006054046,0.0002593609,0.000861755,0.0003549476,0.001624819,0.0003063698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003872542,"about_ca_system_score_gemma":0.0004668358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009914057,"about_ca_topic_score_gemma":0.001447665,"domain_scores_codex":[0.9989786,0.0003053753,0.0001618003,0.0001688229,0.0002145475,0.0001707364],"domain_scores_gemma":[0.9943178,0.002374609,0.001908293,0.0004207996,0.0003440459,0.0006344175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02179074,0.0004405891,0.9396238,0.0001672962,0.002256884,0.0006352272,0.0001414206,0.0005565872,0.001266499,0.0003464819,0.0007721983,0.03200224],"study_design_scores_gemma":[0.0001953677,0.001791713,0.9942614,0.00004446162,0.001079435,0.0004817376,0.0001200539,0.0006287401,0.0001998386,0.0003462897,0.0008277604,0.00002318362],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9855527,0.007881992,0.0001987528,0.0008335994,0.0001675112,0.00001258623,0.0004729612,0.00000927923,0.004870568],"genre_scores_gemma":[0.9977239,0.001019646,0.00008771081,0.0002715088,0.0003127877,0.000005298089,0.0002881527,0.000005404321,0.0002856152],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0018478,"threshold_uncertainty_score":0.006181538,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02433357033887436,"score_gpt":0.2934884938865033,"score_spread":0.269154923547629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}