{"id":"W3181415682","doi":"10.3390/cells10071761","title":"Cytokine Storm Syndrome in SARS-CoV-2 Infections: A Functional Role of Mast Cells","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Colleges and Universities","keywords":"Cytokine storm; Cytokine; Immune system; Immunology; Medicine; Cytokine release syndrome; Inflammation; Coronavirus; Mast cell; Disease; Immunotherapy; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty); Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0005041944,0.0005051179,0.002341859,0.0009875216,0.00005120417,0.000033659,0.0002535072,0.0005635497,0.0001537475],"category_scores_gemma":[0.0001060377,0.0004482012,0.0008106548,0.001519621,0.0001562089,0.00008243013,0.0002107216,0.001119467,0.0007947178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005397911,"about_ca_system_score_gemma":0.001788763,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003183941,"about_ca_topic_score_gemma":0.0001132473,"domain_scores_codex":[0.9968457,0.0002055451,0.0009782288,0.0007053248,0.0007298868,0.000535327],"domain_scores_gemma":[0.9982719,0.0003417399,0.0002922608,0.0008002486,0.0002393651,0.00005446715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001802387,0.0067505,0.001007027,0.11984,0.001975213,0.00403021,0.0003731013,0.000003578288,0.1672162,0.0003503771,0.011025,0.6872485],"study_design_scores_gemma":[0.0007279583,0.0002612062,0.00002994198,0.008597362,0.0004438657,0.0005059572,0.00004043376,0.000007629708,0.03084587,0.00002308299,0.9581962,0.0003204927],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005193323,0.9887273,0.00002851729,0.00001539845,0.0006049296,0.001190019,0.0001122646,0.00005164815,0.004076605],"genre_scores_gemma":[0.001129068,0.9949538,0.0001028956,0.002033435,0.0004602253,0.0003946762,0.000150326,0.0001759399,0.0005996097],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9471712,"threshold_uncertainty_score":0.9999833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07009913570487042,"score_gpt":0.3583834696433927,"score_spread":0.2882843339385223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}