{"id":"W3181415682","doi":"10.3390/cells10071761","title":"Cytokine Storm Syndrome in SARS-CoV-2 Infections: A Functional Role of Mast Cells","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Ministry of Colleges and Universities","keywords":"Cytokine storm; Cytokine; Immune system; Immunology; Medicine; Cytokine release syndrome; Inflammation; Coronavirus; Mast cell; Disease; Immunotherapy; Coronavirus disease 2019 (COVID-19); Infectious disease (medical specialty); Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003642025,0.0005965682,0.0009122043,0.001697057,0.0002273586,0.0007919732,0.000451427,0.0008937534,0.002550565],"category_scores_gemma":[0.0006094809,0.0001667229,0.0004931422,0.001346726,0.0003225183,0.000990927,0.0004792607,0.001452245,0.0009541592],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003967143,"about_ca_system_score_gemma":0.0008633894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007606898,"about_ca_topic_score_gemma":0.001249067,"domain_scores_codex":[0.9998729,0.00002470319,0.00002156631,0.00002008331,0.00004657891,0.00001403718],"domain_scores_gemma":[0.9997819,0.0001087036,0.0000321818,0.000005911961,0.00005393315,0.00001734253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001142883,0.00006208953,0.0002540214,0.02725453,0.0001189044,0.0002872124,0.0001045569,0.0002893991,0.002330392,0.003717731,0.03509132,0.9303755],"study_design_scores_gemma":[0.00002120589,0.0001246836,0.001122345,0.006296754,0.0001562719,0.00215687,0.00007596047,0.00007745327,0.0004345993,0.001865286,0.9876523,0.0000161565],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000107,0.9985912,0.00007653412,0.0002431456,0.000209794,0.000003951075,0.000013844,0.000005389952,0.0007491304],"genre_scores_gemma":[0.000682734,0.998384,0.000111206,0.0001886204,0.0001462333,0.000005227377,0.00002468347,9.642279e-7,0.0004563649],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002550565,"threshold_uncertainty_score":0.008532524,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07009913570487042,"score_gpt":0.3583834696433927,"score_spread":0.2882843339385223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}