{"id":"W3181611529","doi":"10.2196/29912","title":"First-line Advanced Cutaneous Melanoma Treatments: Where Do We Stand?","year":2021,"lang":"en","type":"article","venue":"JMIR Cancer","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Clinical trial; Intensive care medicine; Adverse effect; Melanoma; Immunotherapy; Randomized controlled trial; Scarcity; Surgery; Cancer; Internal medicine; Cancer research","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0000428177,0.0002105198,0.0003815622,0.00006482196,0.00008391737,0.00003453214,0.00009463915,0.0001123706,0.04304577],"category_scores_gemma":[0.00002255419,0.0001763641,0.000150327,0.0003495971,0.00005827206,0.00006400773,0.00005727606,0.0002480998,0.0001477516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007025948,"about_ca_system_score_gemma":0.0004544588,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007649173,"about_ca_topic_score_gemma":0.0006577966,"domain_scores_codex":[0.9983912,0.00003784321,0.0002230477,0.0004387213,0.0004811697,0.0004280217],"domain_scores_gemma":[0.9988585,0.00007692324,0.00005183417,0.0005615597,0.0002265146,0.0002247336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.003383244,0.0008090513,0.009963667,0.0007538185,0.0008724561,0.005688016,0.001322837,0.0001916236,0.08527066,0.00007749561,0.01933055,0.8723366],"study_design_scores_gemma":[0.00446313,0.000612644,0.0008912897,0.0006192029,0.00007881933,0.0003487885,0.0002626448,0.00009332457,0.0160947,0.0001115836,0.9762312,0.0001927028],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"other","genre_scores_codex":[0.711188,0.2328139,0.00005637299,0.02268659,0.0007522412,0.002054988,0.0002541813,0.0002535414,0.02994022],"genre_scores_gemma":[0.297221,0.1564007,0.0007194518,0.0004862901,0.001196619,0.001168805,0.00004281972,0.0001699664,0.5425943],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9569006,"threshold_uncertainty_score":0.957829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02444008506318472,"score_gpt":0.3555394913036441,"score_spread":0.3310994062404594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}