{"id":"W3181980446","doi":"10.1016/j.biochi.2021.07.005","title":"Old dog, new tricks: Influenza A virus NS1 and in vitro fibrillogenesis","year":2021,"lang":"en","type":"article","venue":"Biochimie","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Research Council Canada; National Research Center \"Kurchatov Institute\"","keywords":"Fibrillogenesis; Proteolysis; Fibril; Immune system; In vitro; Chemistry; Protein aggregation; Biochemistry; Protease; Cell biology; Recombinant DNA; Biology; Enzyme; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001887877,0.0001977709,0.0004310434,0.0002420921,0.00008044569,0.00003704424,0.00007424691,0.0001212352,0.0001192235],"category_scores_gemma":[0.0009849821,0.0001735661,0.00009143986,0.0005859752,0.0001048918,0.00007249585,0.0002277227,0.0001948636,0.00009593383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001092734,"about_ca_system_score_gemma":0.0003677531,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005651263,"about_ca_topic_score_gemma":0.000099718,"domain_scores_codex":[0.9984,0.00006888888,0.0003099875,0.0004094098,0.0003549905,0.0004567559],"domain_scores_gemma":[0.9990838,0.0001388079,0.00004452689,0.0003607356,0.0001117523,0.0002604012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001229243,0.0001599034,0.05161043,0.0002095624,0.0002060971,0.0005808971,0.0005975183,0.000003323486,0.9052565,0.00006589619,0.007907089,0.03217353],"study_design_scores_gemma":[0.004424939,0.0001337576,0.1917537,0.0001305998,0.00007151334,0.00008887585,0.0001830364,0.00003038165,0.6612045,0.0001283959,0.1415773,0.0002729575],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9762182,0.0194749,0.00001459244,0.001238917,0.00008156572,0.0003202233,0.00003257246,0.00005699075,0.002562055],"genre_scores_gemma":[0.96356,0.005958899,0.006033202,0.01463427,0.0008784958,0.00008001484,0.0000368433,0.00009594763,0.00872233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.244052,"threshold_uncertainty_score":0.7077821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07454234370576497,"score_gpt":0.3731314297529166,"score_spread":0.2985890860471517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}