{"id":"W3181980446","doi":"10.1016/j.biochi.2021.07.005","title":"Old dog, new tricks: Influenza A virus NS1 and in vitro fibrillogenesis","year":2021,"lang":"en","type":"article","venue":"Biochimie","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Research Council Canada; National Research Center \"Kurchatov Institute\"","keywords":"Fibrillogenesis; Proteolysis; Fibril; Immune system; In vitro; Chemistry; Protein aggregation; Biochemistry; Protease; Cell biology; Recombinant DNA; Biology; Enzyme; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003462458,0.0005239724,0.0004663435,0.0008065638,0.0005411931,0.001362656,0.0004272979,0.0007782043,0.001646141],"category_scores_gemma":[0.001636288,0.0003368685,0.0003581125,0.0005237292,0.00187563,0.002395568,0.0006525213,0.002104576,0.0005033329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007808451,"about_ca_system_score_gemma":0.0003964646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001758931,"about_ca_topic_score_gemma":0.00265569,"domain_scores_codex":[0.9992844,0.0004238192,0.00004906999,0.00006365044,0.00009674465,0.00008235432],"domain_scores_gemma":[0.9987682,0.0007027676,0.0001119229,0.0001504046,0.0001269035,0.0001398021],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008246967,0.001282594,0.01756939,0.002126216,0.0004624341,0.002329094,0.002949858,0.001119487,0.7297872,0.07400531,0.01352465,0.1465968],"study_design_scores_gemma":[0.0004171249,0.004392739,0.06458409,0.0009218866,0.0004125467,0.005552487,0.005322875,0.003203553,0.6411526,0.09010842,0.1836359,0.0002957591],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.3719043,0.553215,0.01252708,0.03789888,0.003885336,0.00005432971,0.0003718765,0.0001453882,0.01999774],"genre_scores_gemma":[0.8661675,0.1120918,0.005764814,0.003177488,0.002384818,0.00003932263,0.0003019778,0.00007347198,0.009998776],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003462458,"threshold_uncertainty_score":0.0183115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07454234370576497,"score_gpt":0.3731314297529166,"score_spread":0.2985890860471517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}