{"id":"W3182190552","doi":"10.1165/rcmb.2021-0049le","title":"Efficient Transduction of Alveolar Type 2 Cells with Adeno-associated Virus for the Study of Lung Regeneration","year":2021,"lang":"en","type":"letter","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"National Heart, Lung, and Blood Institute","keywords":"Regeneration (biology); Transduction (biophysics); Lung; Virus; Virology; Biology; Cell biology; Signal transduction; Medicine; Pathology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002471749,0.0006528408,0.0007764335,0.0004009274,0.0009073669,0.001202438,0.0008016851,0.01090437,0.003380278],"category_scores_gemma":[0.003674408,0.0003809244,0.0007002582,0.0001943901,0.001439437,0.0008614558,0.0004381468,0.008295772,0.002703622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001826059,"about_ca_system_score_gemma":0.0008870089,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008289175,"about_ca_topic_score_gemma":0.001493942,"domain_scores_codex":[0.998525,0.0006058181,0.0001312586,0.00009033609,0.0004934529,0.0001542636],"domain_scores_gemma":[0.9977428,0.001610293,0.0001118115,0.000106559,0.0002752114,0.000153423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00245742,0.0007332958,0.001961831,0.0007513451,0.0001393238,0.01652937,0.0004169937,0.0008455748,0.05851894,0.02845132,0.7948447,0.09434983],"study_design_scores_gemma":[0.0007250906,0.0007672973,0.002929887,0.0001711856,0.00008675612,0.00649003,0.0001674352,0.002748835,0.03101375,0.01067605,0.9441318,0.00009192121],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"empirical","genre_scores_codex":[0.01786418,0.01593169,0.009415001,0.8559402,0.07265468,0.0003235587,0.000424329,0.0003886014,0.02705779],"genre_scores_gemma":[0.1621974,0.02607895,0.01310556,0.5611777,0.09978134,0.0008897835,0.0007744014,0.0003147549,0.1356801],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.01090437,"threshold_uncertainty_score":0.0132491,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01194871773744206,"score_gpt":0.2776440072340207,"score_spread":0.2656952894965787,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}