{"id":"W3182465791","doi":"10.1016/j.stemcr.2021.06.010","title":"Fractalkine signaling regulates oligodendroglial cell genesis from SVZ precursor cells","year":2021,"lang":"en","type":"article","venue":"Stem Cell Reports","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Glycomics Network; Canadian Institutes of Health Research; Agence Nationale de la Recherche; Women and Children's Health Research Institute; CRC Health Group; Multiple Sclerosis Society of Canada; Natural Sciences and Engineering Research Council of Canada; Fondation Brain Canada; University of Alberta","keywords":"Subventricular zone; Oligodendrocyte; CX3CR1; Biology; Cell biology; Chemokine; CX3CL1; Neural stem cell; Microglia; Precursor cell; Neuroscience; Neurogenesis; Immunology; Central nervous system; Stem cell; Cell; Chemokine receptor; Myelin; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001124239,0.0001849519,0.000199707,0.0002396099,0.0001591444,0.0003034391,0.0001071529,0.0002138857,0.0004938655],"category_scores_gemma":[0.0001317266,0.0001016407,0.0001322625,0.0001001676,0.0002000348,0.0002701243,0.0001905277,0.0004658212,0.0001587172],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003165941,"about_ca_system_score_gemma":0.0002351244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006190505,"about_ca_topic_score_gemma":0.001092288,"domain_scores_codex":[0.9998785,0.00001603843,0.0000105807,0.00002393984,0.0000368108,0.00003398938],"domain_scores_gemma":[0.999882,0.0000239758,0.00003300513,0.00000599104,0.0000136949,0.00004128645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000592223,0.000006358532,0.0001946163,0.00002633875,0.000001639937,0.00006387637,0.00002878502,0.0000555675,0.9978248,0.0002892907,0.00003822436,0.001411382],"study_design_scores_gemma":[0.00001434248,0.0001028783,0.01279956,0.00001198048,0.00001230921,0.0003197994,0.00006008846,0.001303763,0.9817115,0.0002616744,0.003394522,0.000007590212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934474,0.002668765,0.002234523,0.000104547,0.00001799778,0.000009184498,0.0002600828,0.00005214271,0.001205372],"genre_scores_gemma":[0.993221,0.001608675,0.002921209,0.00004923463,0.00001521495,0.00001597262,0.0002682264,0.00001674753,0.001883495],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006190505,"threshold_uncertainty_score":0.002297044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01933052593668106,"score_gpt":0.2166258520055522,"score_spread":0.1972953260688712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}