{"id":"W3182474383","doi":"10.1007/s12250-021-00422-7","title":"Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis","year":2021,"lang":"en","type":"article","venue":"Virologica Sinica","topic":"Mosquito-borne diseases and control","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Immunoprecipitation; Neural stem cell; Cell biology; Biology; Progenitor cell; Apoptosis; Microcephaly; Programmed cell death; Cell fate determination; Neurogenesis; Transcription factor; Stem cell; Cell culture; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000103209,0.0002361217,0.0005994946,0.00008985347,0.00006087752,0.00003199232,0.000128542,0.0001599506,0.0002099377],"category_scores_gemma":[0.0001293097,0.0001610366,0.00009828972,0.0002620201,0.0001868226,0.00007180177,0.0001069153,0.0003189355,0.00000503282],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002218027,"about_ca_system_score_gemma":0.0001049097,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000894332,"about_ca_topic_score_gemma":0.00004865374,"domain_scores_codex":[0.9983993,0.0001029071,0.0004546544,0.0004745818,0.0002365917,0.0003320278],"domain_scores_gemma":[0.9990608,0.00008329941,0.0002056062,0.0003417477,0.0001159224,0.0001926993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001094081,0.0003179777,0.01306159,0.00009542976,0.00008506647,0.0001651984,0.0001544831,0.000003606828,0.9831017,0.00002247528,0.00003849833,0.001859843],"study_design_scores_gemma":[0.005759837,0.003132692,0.4033599,0.0002246053,0.0002275567,0.00003979559,0.0003329369,0.0004599401,0.5857379,0.00005392313,0.0003373196,0.000333588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976932,0.0003830804,9.172823e-7,0.0007270383,0.00006016391,0.0008058722,0.00003857951,0.00002982917,0.0002612729],"genre_scores_gemma":[0.9988351,0.0000230907,0.0002020073,0.0005804729,0.0001050094,0.000109964,0.00004570349,0.00002089912,0.00007776148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3973638,"threshold_uncertainty_score":0.6566884,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01281520831654781,"score_gpt":0.2645996650422677,"score_spread":0.2517844567257199,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}