{"id":"W3182719817","doi":"10.1002/jimd.12416","title":"Assessment of intellectual impairment, health‐related quality of life, and behavioral phenotype in patients with neurotransmitter related disorders: Data from the <scp>iNTD</scp> registry","year":2021,"lang":"en","type":"article","venue":"Journal of Inherited Metabolic Disease","topic":"Bipolar Disorder and Treatment","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Stollery Children's Hospital; Hospital for Sick Children; SickKids Foundation; University of Toronto; Glenrose Rehabilitation Hospital; Women and Children’s Health Research Institute; University of Alberta","funders":"Dietmar Hopp Stiftung; Universität Heidelberg; National Institute for Health and Care Research; Children's Health Research Institute; Women and Children's Health Research Institute; PTC Therapeutics; Rosetrees Trust","keywords":"Quality of life (healthcare); Neurotransmitter; Dopamine; Psychology; Medicine; Psychiatry; Clinical psychology; Internal medicine; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001123732,0.0002910452,0.0006807938,0.002431195,0.0003619315,0.0006924939,0.0004485111,0.0004151976,0.001827665],"category_scores_gemma":[0.003508506,0.0001477102,0.0005698611,0.00229509,0.0001918752,0.0005172321,0.0006110232,0.0005321093,0.0005049757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003143076,"about_ca_system_score_gemma":0.0004180675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004135739,"about_ca_topic_score_gemma":0.002764264,"domain_scores_codex":[0.9991928,0.0001850815,0.0002329826,0.0001133635,0.0001823587,0.00009347026],"domain_scores_gemma":[0.9956183,0.0006053788,0.002125277,0.0002968112,0.0008210302,0.0005330832],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007721437,0.00002542777,0.9988045,0.00001028984,0.00002864803,0.00005382572,0.00002405778,0.00003638028,0.00005835382,0.000005861481,0.000235997,0.0006395597],"study_design_scores_gemma":[0.00001246102,0.0000839868,0.9990979,0.000006178408,0.00001733943,0.0002694322,0.00005891209,0.0001133738,0.00005682566,0.000007411275,0.0002725455,0.000003697051],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856991,0.0001751854,0.0001253254,0.00004528573,0.000007634588,0.00007586269,0.01231836,0.00001708527,0.001536151],"genre_scores_gemma":[0.981032,0.0001568953,0.0002726562,0.00004271944,0.0000169128,0.0001864109,0.01793421,0.000007511268,0.0003507008],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004135739,"threshold_uncertainty_score":0.008223295,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0366924533083586,"score_gpt":0.3249767946624032,"score_spread":0.2882843413540446,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}