{"id":"W3182741432","doi":"10.1093/neuonc/noab164","title":"Selumetinib for optic pathway glioma: Seeing through the fog, (not yet) the end of the tunnel?","year":2021,"lang":"en","type":"letter","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Glioma; Selumetinib; Medicine; Internal medicine; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006095367,0.0005480886,0.0006555923,0.0005320563,0.001156538,0.001360628,0.0008595929,0.0107086,0.004125085],"category_scores_gemma":[0.003266808,0.0002462986,0.00074938,0.0003756657,0.001059105,0.002562999,0.0004018802,0.009350098,0.00469837],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002179456,"about_ca_system_score_gemma":0.00101081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002146685,"about_ca_topic_score_gemma":0.004383745,"domain_scores_codex":[0.9994697,0.0001295344,0.00006165556,0.00006267047,0.0001887176,0.00008780908],"domain_scores_gemma":[0.9992757,0.0003064103,0.00005934078,0.00002247768,0.0001322861,0.0002037515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001447854,0.00007995063,0.001475082,0.0001609245,0.00003000824,0.02534182,0.0001036104,0.0002556478,0.0006701549,0.00281888,0.9214206,0.04749864],"study_design_scores_gemma":[0.0002482256,0.000322536,0.002266731,0.0005757343,0.00005915778,0.0803346,0.0003269208,0.001315848,0.001053353,0.0124978,0.9009292,0.00006985755],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002696893,0.01395424,0.0003893793,0.9476905,0.02477017,0.00003862349,0.00009661257,0.00008732472,0.01027618],"genre_scores_gemma":[0.02622163,0.02095494,0.001071395,0.8241819,0.1033194,0.00006977982,0.000119819,0.00007149669,0.02398966],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0107086,"threshold_uncertainty_score":0.01581317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04100559555339472,"score_gpt":0.2994889941255563,"score_spread":0.2584833985721616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}