{"id":"W3182741432","doi":"10.1093/neuonc/noab164","title":"Selumetinib for optic pathway glioma: Seeing through the fog, (not yet) the end of the tunnel?","year":2021,"lang":"en","type":"letter","venue":"Neuro-Oncology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Glioma; Selumetinib; Medicine; Internal medicine; Cancer research; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004031004,0.0005052499,0.001095037,0.00007796026,0.0003658365,0.00004211221,0.000690168,0.0007917419,0.0001978697],"category_scores_gemma":[0.0009233904,0.0002272931,0.0008555347,0.0004111697,0.0005516625,0.00003619973,0.0003601284,0.001701236,0.00002322872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002438767,"about_ca_system_score_gemma":0.0008361203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008086024,"about_ca_topic_score_gemma":0.00004886583,"domain_scores_codex":[0.9965785,0.0007795328,0.0006997907,0.0007096911,0.0005635539,0.0006689283],"domain_scores_gemma":[0.9909436,0.006603385,0.0006331325,0.001502509,0.0002632458,0.00005420442],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001201075,0.000473595,0.0001666115,0.0002959337,0.0007662266,0.003256797,0.001513834,0.00001613586,0.04387957,0.0006650089,0.9438722,0.004974],"study_design_scores_gemma":[0.002522119,0.00101151,0.0003846345,0.0001425514,0.00135286,0.001356988,0.0003263262,0.00002883179,0.04147142,0.0002752092,0.9509457,0.0001818273],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.08784483,0.001759837,0.00001185684,0.9002301,0.003359382,0.002915965,0.0001820159,0.00004511064,0.00365088],"genre_scores_gemma":[0.2910982,0.0002103034,0.0003803826,0.7019056,0.004146978,0.001422372,0.0001980785,0.0001865933,0.0004515379],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.2032533,"threshold_uncertainty_score":0.9268745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04100559555339472,"score_gpt":0.2994889941255563,"score_spread":0.2584833985721616,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}