{"id":"W3182835343","doi":"10.1152/ajpregu.00090.2021","title":"Transient antibiotic-induced changes in the neonatal swine intestinal microbiota impact islet expression profiles reducing subsequent function","year":2021,"lang":"en","type":"article","venue":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Government of Canada; Consejo Nacional de Ciencia y Tecnología; Women and Children's Health Research Institute; Canada Research Chairs; Alberta Innovates","keywords":"Endocrinology; Internal medicine; Biology; Islet; PDX1; Microbiome; Insulin; Dysbiosis; Gut flora; Immunology; Medicine; Bioinformatics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000148144,0.0002278414,0.0002892601,0.000164666,0.0001152187,0.0002893583,0.0001705986,0.0002945106,0.001277737],"category_scores_gemma":[0.0001795206,0.0001240664,0.0002898401,0.000123965,0.0003018642,0.0002000192,0.0002393792,0.0006331342,0.0002235574],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002956396,"about_ca_system_score_gemma":0.0002904692,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007269141,"about_ca_topic_score_gemma":0.001244235,"domain_scores_codex":[0.9997755,0.00002584804,0.00001805066,0.00006807232,0.00003811675,0.00007444202],"domain_scores_gemma":[0.9998332,0.00002147797,0.00005150485,0.0000194548,0.00002015855,0.00005420023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001073007,0.0001038444,0.002645727,0.00003273999,0.000007382514,0.00005697238,0.00002143822,0.00002704608,0.9939952,0.00002357255,0.00004785811,0.001965222],"study_design_scores_gemma":[0.00005980285,0.007229717,0.1804497,0.00002442927,0.00007191955,0.0003721529,0.0003139722,0.0008261838,0.8082858,0.00008762168,0.002261997,0.00001670741],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982692,0.0003604305,0.0003971593,0.00004906214,0.0000256985,0.00001456998,0.0003722121,0.00001312938,0.0004984819],"genre_scores_gemma":[0.9959978,0.0004708488,0.000810169,0.0001663175,0.00001261817,0.00007670445,0.0008887373,0.0000137346,0.001563147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001277737,"threshold_uncertainty_score":0.004274487,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02185131613994963,"score_gpt":0.2968360945325324,"score_spread":0.2749847783925828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}