{"id":"W3183177352","doi":"10.3389/fendo.2021.681646","title":"Mouse Spexin: (I) NMR Solution Structure, Docking Models for Receptor Binding, and Histological Expression at Tissue Level","year":2021,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Health and Medical Research Fund; Directorate for Biological Sciences; University of Alberta","keywords":"Receptor; G protein-coupled receptor; Docking (animal); Homology modeling; Random coil; Biology; Biochemistry; Biophysics; Chemistry; Protein secondary structure; Cell biology; Enzyme; Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006907214,0.0001836221,0.0002735291,0.00008583147,0.0001406723,0.00001574975,0.0001302543,0.0002824584,0.000080606],"category_scores_gemma":[0.00008237708,0.0001802479,0.00005835682,0.0000557452,0.00008494666,0.000009500248,0.0002288696,0.0001293052,0.000001438651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008049879,"about_ca_system_score_gemma":0.00003768899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008579425,"about_ca_topic_score_gemma":0.0000337702,"domain_scores_codex":[0.9985587,0.0000929484,0.0002439895,0.0005699041,0.00008150576,0.0004529388],"domain_scores_gemma":[0.9995537,0.00001405556,0.00009149572,0.0002160341,0.00005605117,0.00006863813],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001473764,0.00002463031,0.0009175439,0.00002122491,0.00002365315,0.00001093576,0.00005752794,0.0005264193,0.9816906,0.0003278819,0.01065923,0.00559293],"study_design_scores_gemma":[0.0009068612,0.0001585488,0.00003409943,0.00001300286,0.0000109465,0.00006308594,0.0001245616,0.001389263,0.9475855,0.00162142,0.04787488,0.0002178581],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7806737,0.004166088,0.2136058,0.0001132179,0.0009848687,0.0002175197,0.0001165134,0.00001663898,0.0001055928],"genre_scores_gemma":[0.8680333,0.001053084,0.1274662,0.0001379956,0.0002346113,0.00005096746,0.0006145503,0.00003547845,0.002373867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08735956,"threshold_uncertainty_score":0.7350298,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02867227447711724,"score_gpt":0.2566379145150908,"score_spread":0.2279656400379735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}