{"id":"W3183228708","doi":"10.15252/embr.202052190","title":"Homologous recombination is reduced in female embryonic stem cells by two active X chromosomes","year":2021,"lang":"en","type":"article","venue":"EMBO Reports","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Institute of Genetics; Hospital Universiti Sains Malaysia; Yasuda Memorial Medical Foundation; Kanazawa University; Kindai University","keywords":"Homologous recombination; Embryonic stem cell; Biology; Homologous chromosome; Cell biology; Genetics; Recombination; Stem cell; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001169109,0.0001295824,0.0001548375,0.00003290644,0.00003238727,0.00001849269,0.00005513817,0.0001138464,0.00006062215],"category_scores_gemma":[0.00002146652,0.000146182,0.00006822526,0.0001199086,0.00001762603,0.000003845248,0.00006773405,0.00009287531,0.000004893347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003516379,"about_ca_system_score_gemma":0.00009776789,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001925815,"about_ca_topic_score_gemma":0.00002695804,"domain_scores_codex":[0.9989874,0.00003524606,0.0002344516,0.0004309878,0.000101495,0.000210376],"domain_scores_gemma":[0.999415,0.000007439547,0.00008904493,0.0003682347,0.00006570519,0.00005462423],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000006286767,0.00006831989,0.0006020129,0.00001613754,0.00002793103,0.0002830875,0.0001384841,0.0002327282,0.9896854,0.000002257899,0.004030786,0.004906528],"study_design_scores_gemma":[0.0002517726,0.00005720936,0.001375078,0.00001616062,0.000009234963,0.0002981747,0.0001439243,0.0000360822,0.988946,0.00004263603,0.008653896,0.0001698234],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954454,0.001862054,0.0002664367,0.0001324084,0.0004891544,0.0001218586,0.000008533709,0.00001426989,0.001659917],"genre_scores_gemma":[0.9931841,0.0002174261,0.0001461904,0.000084712,0.00006759925,0.00002382097,0.00010553,0.0000214514,0.006149151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004736705,"threshold_uncertainty_score":0.5961128,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007324581329542383,"score_gpt":0.2793270476621564,"score_spread":0.272002466332614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}