{"id":"W3183246938","doi":"10.3390/biomedicines9070831","title":"IL-17A Damages the Blood–Retinal Barrier through Activating the Janus Kinase 1 Pathway","year":2021,"lang":"en","type":"article","venue":"Biomedicines","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University Belfast; Diabetes UK; Queen's University; British Heart Foundation","keywords":"Cell biology; Retinal; Blood–retinal barrier; Chemistry; Biology; Biochemistry; Endocrinology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001682845,0.0002347457,0.0002796769,0.0000336192,0.0003717686,0.00004562747,0.0001609656,0.00006465335,0.0004823538],"category_scores_gemma":[0.0004089559,0.0001038278,0.0001729592,0.0004559299,0.0003673086,0.00007276568,0.0001011829,0.0001938663,0.00004514495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002559216,"about_ca_system_score_gemma":0.0002012623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001198683,"about_ca_topic_score_gemma":0.000007042205,"domain_scores_codex":[0.9984593,0.0001135509,0.0002700408,0.0003324414,0.0004883649,0.0003363267],"domain_scores_gemma":[0.9986418,0.000288517,0.0001081193,0.0006239445,0.0001857082,0.0001519338],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001561864,0.003811148,0.3347156,0.001171334,0.004114266,0.01784846,0.009654861,0.000003656477,0.4089695,0.007335389,0.04740839,0.1634055],"study_design_scores_gemma":[0.006314251,0.001089332,0.4579623,0.001449877,0.002040851,0.001700661,0.01119307,0.00007941313,0.09758776,0.001580262,0.4185066,0.000495594],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.960519,0.007403297,0.00003616679,0.02322163,0.0004077435,0.0003977302,0.0000658276,0.00006737918,0.007881243],"genre_scores_gemma":[0.9894552,0.0005050243,0.0002653755,0.002726877,0.0009866678,0.00005416845,0.0001055501,0.00003058997,0.005870568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3710982,"threshold_uncertainty_score":0.5281436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02238260643825465,"score_gpt":0.289010382721972,"score_spread":0.2666277762837174,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}