{"id":"W3183252456","doi":"10.1101/2021.07.16.21260656","title":"Elevated levels of the cytokine LIGHT in Crohn’s disease","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cerecor","keywords":"Cytokine; Medicine; Crohn's disease; Disease; Antibody; Tumor necrosis factor alpha; Inflammatory bowel disease; Immunology; Cohort; Internal medicine; Receptor; Gastroenterology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003386177,0.0002285614,0.0002554218,0.0005946165,0.0001724474,0.0004113404,0.0001062027,0.0002464315,0.00176418],"category_scores_gemma":[0.0007468463,0.0001265765,0.0001144714,0.0003479457,0.0002310647,0.0001325382,0.0002283335,0.0003663689,0.0002629478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001239746,"about_ca_system_score_gemma":0.00007111286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002444774,"about_ca_topic_score_gemma":0.0001961742,"domain_scores_codex":[0.9997563,0.0000735316,0.00002177503,0.00005709611,0.00006028556,0.0000309221],"domain_scores_gemma":[0.9993519,0.0002025853,0.0002092837,0.00004095402,0.00006980127,0.0001254374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002760742,0.00008054535,0.8572734,0.0001064077,0.00009838064,0.001215927,0.0002448718,0.0001381372,0.1233417,0.0001070169,0.0007862547,0.01384667],"study_design_scores_gemma":[0.00003395309,0.0003584015,0.9794586,0.00001547578,0.00004754589,0.00357758,0.0001301029,0.000300628,0.01449169,0.0001814424,0.001397789,0.00000689829],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997707,0.001131115,0.0003747602,0.00005453386,0.00001489234,0.000002638035,0.0003038361,0.00001635988,0.000394727],"genre_scores_gemma":[0.9990024,0.0001290898,0.000396628,0.00002512477,0.00001871464,0.000002135648,0.0002176904,0.000005248313,0.0002030635],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00176418,"threshold_uncertainty_score":0.005901754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01260054672483395,"score_gpt":0.2437136826513394,"score_spread":0.2311131359265054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}