{"id":"W3183537392","doi":"10.2174/1574884716666210726104424","title":"A Systematic Review and Meta-Analysis of the Safety of Hydroxychloroquinein a Randomized Controlled Trial and Observational Studies","year":2021,"lang":"en","type":"review","venue":"Current Reviews in Clinical and Experimental Pharmacology","topic":"Drug-Induced Ocular Toxicity","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Hydroxychloroquine; Observational study; Meta-analysis; Internal medicine; Randomized controlled trial; Placebo; Subgroup analysis; Relative risk; Systematic review; MEDLINE; Coronavirus disease 2019 (COVID-19); Disease; Confidence interval; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","metaepi_broad"],"consensus_categories":[],"category_scores_codex":[0.01154815,0.0005710746,0.0531311,0.0001785671,0.00004189148,0.000005976488,0.0001898167,0.0002093833,0.0001403555],"category_scores_gemma":[0.00660245,0.0002549618,0.00823291,0.0006578708,0.001000269,0.00003827199,0.0004252791,0.0006231458,8.136079e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000488648,"about_ca_system_score_gemma":0.0001717678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002308135,"about_ca_topic_score_gemma":0.000001423049,"domain_scores_codex":[0.9804928,0.009942869,0.00841122,0.0006575095,0.000310622,0.0001849436],"domain_scores_gemma":[0.9886618,0.006858925,0.003777186,0.0004269473,0.0001442305,0.0001309549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01878316,0.0009899292,0.000003181171,0.7461807,0.2307251,0.000003892721,0.00006274813,7.336301e-8,0.000002431364,0.0001262831,0.0001628547,0.002959748],"study_design_scores_gemma":[0.219157,0.00007770391,5.212207e-7,0.0612926,0.7092435,0.00001172378,0.00001167652,0.00001230304,0.000002738525,0.000004674228,0.01004205,0.0001434585],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003288155,0.9719128,9.806577e-7,0.0002387023,0.0005061284,0.0269526,0.00004057333,0.000003904359,0.00001551321],"genre_scores_gemma":[0.0001121058,0.9939155,0.00004900017,0.0005712003,0.00006609737,0.005174439,0.00004032484,0.0000155179,0.00005578966],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6848881,"threshold_uncertainty_score":0.9999903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4514407114423686,"score_gpt":0.5813705809018361,"score_spread":0.1299298694594676,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}