{"id":"W3183573851","doi":"10.3390/cells10081851","title":"The Expanding Role of Mitochondria, Autophagy and Lipophagy in Steroidogenesis","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cholesterol side-chain cleavage enzyme; Pregnenolone; Mitochondrion; Cell biology; Autophagy; Steroidogenic acute regulatory protein; Biology; Inner mitochondrial membrane; Context (archaeology); Chemistry; Biochemistry; Hormone; Enzyme; Steroid; Cytochrome P450; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002346813,0.0002718664,0.001707377,0.0001467904,0.00004127205,0.00003162765,0.0001385717,0.000228918,0.00003781047],"category_scores_gemma":[0.00004822452,0.0001724485,0.0003086709,0.000267133,0.00007386437,0.00002793256,0.0001224546,0.0002847791,0.00001512454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003638604,"about_ca_system_score_gemma":0.0001755826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002518541,"about_ca_topic_score_gemma":0.00001020861,"domain_scores_codex":[0.9984449,0.0001579498,0.0006201181,0.0003389218,0.0001868179,0.0002513221],"domain_scores_gemma":[0.9988639,0.0002781097,0.0002294114,0.0004845375,0.00003771493,0.0001062695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005979422,0.00004329207,0.000008104584,0.004226182,0.00007761974,0.00002220574,0.0001714869,7.560116e-8,0.001291906,0.00003023805,0.0001292283,0.9939937],"study_design_scores_gemma":[0.000442276,0.0000266137,0.00006191853,0.007716526,0.000603351,0.00006176723,0.0001119121,0.00000180447,0.00197311,0.000008012405,0.9888613,0.0001314453],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002234931,0.9960536,0.000001495015,0.00001199917,0.0007345689,0.0005170956,0.0000130449,0.00001027582,0.0004230311],"genre_scores_gemma":[0.00008994521,0.9963456,0.00008984369,0.00002910615,0.0004862407,0.00005215492,0.00001850201,0.00004268547,0.0028459],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9938622,"threshold_uncertainty_score":0.7032244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02289001736402515,"score_gpt":0.3174463620900168,"score_spread":0.2945563447259917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}