{"id":"W3183573851","doi":"10.3390/cells10081851","title":"The Expanding Role of Mitochondria, Autophagy and Lipophagy in Steroidogenesis","year":2021,"lang":"en","type":"review","venue":"Cells","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":78,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cholesterol side-chain cleavage enzyme; Pregnenolone; Mitochondrion; Cell biology; Autophagy; Steroidogenic acute regulatory protein; Biology; Inner mitochondrial membrane; Context (archaeology); Chemistry; Biochemistry; Hormone; Enzyme; Steroid; Cytochrome P450; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003942209,0.0005311154,0.0008711615,0.001966165,0.0003527971,0.001009767,0.0004785983,0.0009742373,0.001992977],"category_scores_gemma":[0.000441453,0.0001711949,0.0003844859,0.001769562,0.0004948315,0.001472398,0.0007362335,0.001412955,0.0008723214],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006807529,"about_ca_system_score_gemma":0.001122572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008825345,"about_ca_topic_score_gemma":0.001606335,"domain_scores_codex":[0.9998485,0.00002876903,0.0000271374,0.00002492748,0.00005364107,0.00001698069],"domain_scores_gemma":[0.999813,0.00008501906,0.00002427,0.000007109216,0.0000483852,0.00002216721],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007196642,0.0000441477,0.0002910388,0.01964931,0.00009757926,0.0005342494,0.0001423174,0.0003654564,0.004208086,0.009821193,0.02609444,0.9386802],"study_design_scores_gemma":[0.00000811545,0.00006491999,0.001305272,0.003015167,0.0000779349,0.00254362,0.00009192648,0.00009348041,0.0007507055,0.003637535,0.9883912,0.00002022683],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001599926,0.9982249,0.0001484491,0.0003701803,0.000203124,0.000002270997,0.00001242764,0.000007203117,0.0008714583],"genre_scores_gemma":[0.0007478739,0.9984124,0.00015637,0.0001408539,0.0001639825,0.000002965134,0.00001715209,0.000001007117,0.0003573322],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001992977,"threshold_uncertainty_score":0.006667137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02289001736402515,"score_gpt":0.3174463620900168,"score_spread":0.2945563447259917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}