{"id":"W3183575767","doi":"10.1182/blood.2020008238","title":"Immune cells surveil aberrantly sialylated <i>O</i>-glycans on megakaryocytes to regulate platelet count","year":2021,"lang":"en","type":"article","venue":"Blood","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute","keywords":"Thrombopoiesis; Immune system; Antigen; Immunology; Biology; Antibody; Molecular biology; Megakaryocyte; Cell biology; Stem cell; Progenitor cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001145776,0.0002070096,0.0001655945,0.0001695669,0.0001141185,0.0003313756,0.00009559678,0.0002290151,0.0008330132],"category_scores_gemma":[0.00009348674,0.0001169599,0.0001675113,0.00009069128,0.0001498918,0.0001470945,0.0001819775,0.0004593972,0.0003499445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000170943,"about_ca_system_score_gemma":0.0001091574,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001940713,"about_ca_topic_score_gemma":0.0003263975,"domain_scores_codex":[0.9998862,0.00001555399,0.00000936588,0.00002679423,0.0000245192,0.00003749093],"domain_scores_gemma":[0.9999157,0.00001167094,0.00002627247,0.000009290291,0.00001268803,0.00002442373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006217851,0.000005728647,0.0007054082,0.00001561129,0.00000243576,0.0000652982,0.00001765339,0.00002532921,0.9981793,0.00008242572,0.00003672887,0.0008019195],"study_design_scores_gemma":[0.00002467904,0.000245395,0.04265315,0.00001728938,0.00003117958,0.0005415265,0.0001176973,0.001293321,0.9516356,0.0001637571,0.003270144,0.000006120397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936752,0.001327754,0.002582462,0.00009763876,0.0000258891,0.00002238829,0.0004198346,0.00008557586,0.001763165],"genre_scores_gemma":[0.9950044,0.0006411243,0.001992612,0.0001463417,0.00001958185,0.00003936179,0.000432588,0.00002171535,0.001702331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008330132,"threshold_uncertainty_score":0.002786696,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01061074405434467,"score_gpt":0.2343741000045405,"score_spread":0.2237633559501958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}