{"id":"W3183597618","doi":"10.20944/preprints202107.0244.v1","title":"Transporters Beam Signals from Cell Membranes","year":2021,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Cholesterol and Lipid Metabolism","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Heart and Stroke Foundation of Canada","keywords":"Cell biology; Membrane; Cytoplasm; Lipid microdomain; Transporter; ATP-binding cassette transporter; Cell signaling; Cell; Cell membrane; Chemistry; Signal transduction; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0004422295,0.0006580893,0.001440643,0.0001844662,0.00007047495,0.0000427878,0.000525118,0.000718003,0.00779523],"category_scores_gemma":[0.00008159414,0.0006464941,0.0008180582,0.0001574661,0.0001208247,0.0001036282,0.0006582944,0.001670497,0.0009546907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008248864,"about_ca_system_score_gemma":0.0004065459,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001103417,"about_ca_topic_score_gemma":0.00003528222,"domain_scores_codex":[0.9960558,0.000128273,0.0009145748,0.001682154,0.0006983681,0.0005207994],"domain_scores_gemma":[0.9966757,0.00009543162,0.000345334,0.002187252,0.0002142394,0.0004820282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002889371,0.000867112,0.4073331,0.001547636,0.0006406447,0.0003766645,0.005418193,0.0004320968,0.5817243,0.000003171784,0.0001034728,0.00126466],"study_design_scores_gemma":[0.001549828,0.00001408107,0.5381204,0.0006550425,0.0008816393,0.00001500876,0.0003660854,0.00002600586,0.4400743,0.00009894017,0.01771473,0.0004838387],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9837953,0.002824744,0.0001095496,0.0009191689,0.002088418,0.000895201,0.0001270579,0.0002865853,0.008953944],"genre_scores_gemma":[0.9896497,0.001474444,0.0003114318,0.001345442,0.001451742,0.0001433105,0.001013561,0.0001145877,0.004495755],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1416499,"threshold_uncertainty_score":0.9998232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09020005241060261,"score_gpt":0.3194404441179082,"score_spread":0.2292403917073056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}