{"id":"W3183637498","doi":"10.7150/thno.62256","title":"Twist1 contributes to developing and sustaining corticosteroid resistance in ulcerative colitis","year":2021,"lang":"en","type":"article","venue":"Theranostics","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Ulcerative colitis; Colitis; Inflammation; STAT protein; Inflammatory bowel disease; STAT3; Corticosteroid; Glucocorticoid receptor; Glucocorticoid; Medicine; Activator (genetics); Apoptosis; Immunology; Receptor; Chemistry; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001496986,0.0004065502,0.0002363895,0.0002674729,0.0002515691,0.0003420884,0.0001940334,0.0003842837,0.001894859],"category_scores_gemma":[0.0002111386,0.0001214639,0.0002248128,0.0001957413,0.0004065479,0.0001813031,0.0002674619,0.0005581367,0.0002813726],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000269426,"about_ca_system_score_gemma":0.0002249753,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003447061,"about_ca_topic_score_gemma":0.0004401317,"domain_scores_codex":[0.9998884,0.0000219612,0.000009887005,0.0000237039,0.00001876535,0.00003730154],"domain_scores_gemma":[0.9997783,0.00001886979,0.0001189512,0.00001067361,0.00001434732,0.0000589286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003737535,0.0001880155,0.05601194,0.001511601,0.000107154,0.004327223,0.0002287828,0.0005646764,0.8871845,0.001669265,0.002017956,0.04245128],"study_design_scores_gemma":[0.0004403614,0.003943514,0.6104483,0.000465042,0.0006266359,0.02623597,0.001271998,0.005029057,0.3034993,0.00250662,0.04542543,0.0001079848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727194,0.02229728,0.001613094,0.0007437159,0.00008004179,0.00004994891,0.0003531944,0.0001156076,0.00202774],"genre_scores_gemma":[0.9942786,0.004050233,0.0003459852,0.000100592,0.00003804016,0.00001759708,0.0001430878,0.000005582022,0.001020319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001894859,"threshold_uncertainty_score":0.006338954,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163493764809627,"score_gpt":0.2481862986975613,"score_spread":0.2365513610494651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}