{"id":"W3183637498","doi":"10.7150/thno.62256","title":"Twist1 contributes to developing and sustaining corticosteroid resistance in ulcerative colitis","year":2021,"lang":"en","type":"article","venue":"Theranostics","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Ulcerative colitis; Colitis; Inflammation; STAT protein; Inflammatory bowel disease; STAT3; Corticosteroid; Glucocorticoid receptor; Glucocorticoid; Medicine; Activator (genetics); Apoptosis; Immunology; Receptor; Chemistry; Cancer research; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001953306,0.0000906135,0.0001849154,0.00006599199,0.00006770317,0.00002729168,0.00004999216,0.00009356577,0.00001663013],"category_scores_gemma":[0.0006167338,0.00009294763,0.0000137173,0.0001635261,0.00005875632,0.00004990407,0.00005021953,0.0001167107,0.00002074754],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007600075,"about_ca_system_score_gemma":0.000147565,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001251002,"about_ca_topic_score_gemma":0.0004747661,"domain_scores_codex":[0.9991391,0.0002360648,0.0002325891,0.0001494951,0.00001816765,0.0002245713],"domain_scores_gemma":[0.9992952,0.0003915781,0.00004245815,0.0001125269,0.0001482542,0.000009921997],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00239871,0.00004577383,0.005403655,0.00006746595,0.0001743109,0.0001393921,0.01144687,0.00001235075,0.866776,0.1028244,0.000901993,0.00980906],"study_design_scores_gemma":[0.002746495,0.00008055138,0.280835,0.0003842586,0.00002400893,0.00003292639,0.002568394,0.000005657243,0.5950582,0.003826303,0.1141506,0.0002876924],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877788,0.004919348,0.003821458,0.002533513,0.0002077253,0.0001938823,0.000005876545,0.00005930381,0.0004801021],"genre_scores_gemma":[0.9971002,0.0002436884,0.0004758727,0.0007629944,0.000008756163,0.00001373377,0.00002853005,0.00001695444,0.001349313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2754313,"threshold_uncertainty_score":0.3790294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163493764809627,"score_gpt":0.2481862986975613,"score_spread":0.2365513610494651,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}