{"id":"W3183827992","doi":"10.1080/19490976.2021.1949097","title":"Enzymatically synthesized exopolysaccharide of a probiotic strain <i>Leuconostoc mesenteroides</i> NTM048 shows adjuvant activity to promote IgA antibody responses","year":2021,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"ASTER","funders":"Japan Agency for Medical Research and Development; Institute for Fermentation, Osaka","keywords":"Leuconostoc mesenteroides; Glucan; Ovalbumin; Recombinant DNA; Biochemistry; Biology; Polysaccharide; Microbiology; Glycoside hydrolase; Escherichia coli; Enzyme; Antigen; Chemistry; Bacteria; Lactic acid; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009578851,0.0004232589,0.0001459622,0.0001190073,0.00006269471,0.0001128918,0.0001134485,0.000174747,0.0006188393],"category_scores_gemma":[0.0001197435,0.00006656826,0.0002765827,0.0001388961,0.0000894096,0.0001103393,0.0001434095,0.0002051348,0.0002211771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001710116,"about_ca_system_score_gemma":0.0001419237,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004662524,"about_ca_topic_score_gemma":0.0006733391,"domain_scores_codex":[0.9999406,0.00001191319,0.000006534973,0.000009628312,0.00001641676,0.00001483571],"domain_scores_gemma":[0.9999419,0.000006697109,0.00002198525,0.000006394426,0.0000092809,0.00001370608],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004374116,0.00001119449,0.0001118945,0.00001465514,0.000001664059,0.00001858964,0.000002409851,0.00002491685,0.999222,0.000008332381,0.000007213888,0.000533425],"study_design_scores_gemma":[0.000007120792,0.0003222895,0.002453099,0.000004207253,0.000008239272,0.0001441248,0.00001119409,0.0001990913,0.9960366,0.00000859364,0.0008029343,0.000002507777],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973291,0.000255387,0.001449588,0.00003382756,0.00001690963,0.0000184383,0.0002349843,0.00002536376,0.0006363786],"genre_scores_gemma":[0.9929288,0.0002175645,0.004438939,0.00002840494,0.000005034142,0.0000175275,0.0009651271,0.00001490641,0.00138366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006188393,"threshold_uncertainty_score":0.002070248,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01618731980384715,"score_gpt":0.267200116151239,"score_spread":0.2510127963473919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}