{"id":"W3183897315","doi":"10.1016/j.jlr.2021.100097","title":"S-palmitoylation of NOD2 controls its localization to the plasma membrane","year":2021,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; University of Toronto; St. Michael's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Palmitoylation; NOD2; Chemistry; Kinase; Biochemistry; Cell biology; Molecular biology; Biology; Receptor; Cysteine; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00104218,0.00005908394,0.0001409907,0.0001030284,0.00006820437,0.00002694568,0.0002550152,0.0001680943,0.00004172992],"category_scores_gemma":[0.0007954861,0.00004013731,0.00007059994,0.0003162951,0.0000620714,0.000002886962,0.0001387213,0.0001987244,0.000007063275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001226077,"about_ca_system_score_gemma":0.0002188323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002181235,"about_ca_topic_score_gemma":0.00002049596,"domain_scores_codex":[0.9988188,0.0002267744,0.0003222902,0.0001168891,0.0003412509,0.000173976],"domain_scores_gemma":[0.9981972,0.0000426601,0.0001310109,0.0002074274,0.001357753,0.00006393508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002024203,0.00004939075,0.0002081882,0.00001461448,0.00004374047,0.000004346403,0.00002940987,0.0006139235,0.9935231,0.000104774,0.001996369,0.003209742],"study_design_scores_gemma":[0.0003939965,0.0005122574,0.0005281547,0.00002049938,0.000006503612,0.00005126041,0.00007319175,0.0002071789,0.8376653,0.00002154628,0.1604825,0.00003756294],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912497,0.0006834847,0.00137803,0.005770142,0.0004008173,0.0001348882,0.000009735155,0.000001275135,0.0003719203],"genre_scores_gemma":[0.9973792,0.0008642167,0.0003145462,0.00009351137,0.0009292435,0.000002308693,0.000008838557,0.000008904735,0.000399244],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1584861,"threshold_uncertainty_score":0.1636752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03402779247056437,"score_gpt":0.3303945135400426,"score_spread":0.2963667210694782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}