{"id":"W3184080378","doi":"10.1016/j.xpro.2021.100698","title":"Protocol for detecting plastic changes in defined neuronal populations in neuropathic mice","year":2021,"lang":"en","type":"article","venue":"STAR Protocols","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hotchkiss Brain Institute; Alberta Children's Hospital; University of Calgary","funders":"Canadian Institutes of Health Research; Canada Research Chairs; International Development Research Centre","keywords":"Optogenetics; Neuroscience; Neuropathic pain; Neurotransmission; Synaptic plasticity; Biological neural network; Electrophysiology; Neuroplasticity; Premovement neuronal activity; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004650403,0.000168781,0.0001956346,0.0002395169,0.0001350057,0.0001029314,0.0002772215,0.00007489554,0.0001036851],"category_scores_gemma":[0.005353882,0.0001724052,0.0000482521,0.0007993961,0.00005193229,0.00009382005,0.0001518742,0.0003572698,0.00001466268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008397266,"about_ca_system_score_gemma":0.0002675542,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002518786,"about_ca_topic_score_gemma":0.001703572,"domain_scores_codex":[0.9976401,0.0005168965,0.0003371208,0.0005857572,0.0003626802,0.0005574393],"domain_scores_gemma":[0.998708,0.0007890616,0.00007999586,0.0002484965,0.00008066244,0.00009383043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003799086,0.0002600848,0.009034864,0.0003255462,6.134396e-7,0.00005817174,0.0001670572,0.0002729182,0.9871427,0.0003168232,0.00003027285,0.002011079],"study_design_scores_gemma":[0.002961849,0.0004687562,0.01570672,0.0002354006,0.000001249467,0.00001347124,0.00002682081,0.009794866,0.9611489,0.001202523,0.008195968,0.0002434474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.107464,5.464005e-7,0.0002358695,0.0001845127,0.00006557556,0.8917121,0.00005766105,0.00004669137,0.0002330083],"genre_scores_gemma":[0.09201978,1.416022e-7,0.0008653902,0.0001417397,0.00005886574,0.9068125,0.000003310194,0.00003418,0.00006411608],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02599374,"threshold_uncertainty_score":0.7030479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2441449323013379,"score_gpt":0.439471543226663,"score_spread":0.1953266109253251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}