{"id":"W3184315968","doi":"10.1016/j.bbmt.2015.02.025","title":"Measuring Therapeutic Response in Chronic Graft-versus-Host Disease. National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: IV. The 2014 Response Criteria Working Group Report","year":2015,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":419,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Institute of Child Health and Human Development; National Cancer Institute; Pharmacyclics; National Center for Advancing Translational Sciences; Health Resources and Services Administration; U.S. Food and Drug Administration; Universitätsklinikum Hamburg-Eppendorf; National Institutes of Health; Universität Regensburg; Amgen; José Carreras Leukämie-Stiftung; Università degli Studi di Genova; Children's National Hospital; Pediatric Blood and Marrow Transplant Consortium; Huntsman Cancer Institute; Therakos; American Society for Blood and Marrow Transplantation; Bristol-Myers Squibb; Center for Cancer Research","keywords":"Medicine; Clinical trial; Host response; Disease; Intensive care medicine; Population; Graft-versus-host disease; Immunology; Pathology; Immune system; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01930752,0.0002820168,0.000912387,0.0004440031,0.0001032364,0.00001494483,0.0001215488,0.0001891427,0.000006852885],"category_scores_gemma":[0.001993478,0.0002229932,0.0001597785,0.0002353556,0.0003417419,0.00006850853,0.00001170043,0.0002041621,0.000001074442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003351289,"about_ca_system_score_gemma":0.00460487,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007245446,"about_ca_topic_score_gemma":0.0003264385,"domain_scores_codex":[0.992638,0.003917903,0.002145701,0.0005551146,0.0003810424,0.0003622312],"domain_scores_gemma":[0.9924902,0.006221135,0.0006932688,0.0002436938,0.0001773054,0.0001743522],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7382851,0.0009487882,0.05115737,0.004062708,0.0007241958,0.0002854961,0.004119872,0.00004461027,0.1966605,0.0008160336,0.0001287859,0.002766493],"study_design_scores_gemma":[0.06959546,0.007048427,0.9019704,0.005477432,0.001253454,0.0001486056,0.0005700667,0.0005323648,0.01029971,0.000245027,0.002237807,0.0006211742],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9889354,0.004870286,0.0006469302,0.002009966,0.0007646012,0.002531641,0.0001914996,0.00003064102,0.00001900944],"genre_scores_gemma":[0.9963266,0.001739639,0.0007982199,0.00008971588,0.0001402919,0.0002767245,0.0005927353,0.0000258054,0.00001027884],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8508131,"threshold_uncertainty_score":0.90934,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.304353186902085,"score_gpt":0.4519394511172288,"score_spread":0.1475862642151439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}