{"id":"W3184360368","doi":"10.1139/cjc-2021-0150","title":"The stabilized iminium catalyzed (<i>E</i>)-polyene cyclization: trapping of non-activated terminating groups enabled by cation–π interactions","year":2021,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Plant biochemistry and biosynthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Chemistry; Polyene; Catalysis; Iminium; Hydrazide; Reactivity (psychology); Bicyclic molecule; Anthracene; Medicinal chemistry; Combinatorial chemistry; Polymer chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006504299,0.000283879,0.0002054182,0.00008330684,0.0001778859,0.0003576575,0.0003927158,0.0002967991,0.002509034],"category_scores_gemma":[0.0001018358,0.0001273232,0.0001580965,0.00007402765,0.0002147184,0.0002873777,0.0002337983,0.0003916906,0.0004062372],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002902026,"about_ca_system_score_gemma":0.0001581416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006356954,"about_ca_topic_score_gemma":0.0008841268,"domain_scores_codex":[0.9999726,0.000002285914,9.826879e-7,0.000007527466,0.000005374202,0.00001126937],"domain_scores_gemma":[0.9999735,0.000005968452,0.000006628518,0.000003875898,0.000002508857,0.000007438342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005683976,0.0002868634,0.0009538889,0.0004861832,0.0000729577,0.0005750245,0.000140677,0.01759344,0.9453819,0.01260756,0.001307339,0.02002571],"study_design_scores_gemma":[0.0003221959,0.001582452,0.001515647,0.00001833025,0.00006691571,0.00026339,0.00007785059,0.09701353,0.8906263,0.001188605,0.007273795,0.00005102305],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9900144,0.0003254107,0.004628385,0.0000715685,0.0000446857,0.00003057651,0.00008425861,0.0001681631,0.004632476],"genre_scores_gemma":[0.99672,0.0001552308,0.001668312,0.00001458827,0.000005533059,0.00001825285,0.0000821432,0.00001540493,0.001320374],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002509034,"threshold_uncertainty_score":0.008393526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005580443947868896,"score_gpt":0.2123656569867816,"score_spread":0.2067852130389127,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}