{"id":"W3184430172","doi":"10.1002/ijc.33748","title":"Characterisation of anal intraepithelial neoplasia and anal cancer in <scp>HIV</scp>‐positive men by immunohistochemical markers p16, Ki‐67, <scp>HPV‐E4</scp> and <scp>DNA</scp> methylation markers","year":2021,"lang":"en","type":"article","venue":"International Journal of Cancer","topic":"Cervical Cancer and HPV Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"KWF Kankerbestrijding","keywords":"Immunohistochemistry; Medicine; Intraepithelial neoplasia; Immunology; Cancer; Internal medicine; Prostate cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003991781,0.000163873,0.0001593744,0.0005726868,0.0002929474,0.0003222091,0.0001362885,0.0002722034,0.0006764022],"category_scores_gemma":[0.0006605709,0.000231823,0.0001627367,0.0003453939,0.0002243804,0.0002521173,0.0002694928,0.0001660724,0.0001451725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001004549,"about_ca_system_score_gemma":0.0001101912,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00099352,"about_ca_topic_score_gemma":0.001477329,"domain_scores_codex":[0.999838,0.00003852752,0.00001553729,0.00004635598,0.00003337577,0.00002824885],"domain_scores_gemma":[0.9996992,0.00006010904,0.0000851237,0.00004065568,0.00005967426,0.00005518315],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001726831,0.00003227372,0.9888502,0.00001604176,0.00002242858,0.000192796,0.0002470637,0.00002668947,0.008192282,0.00001094613,0.00001590834,0.002220632],"study_design_scores_gemma":[0.000002499814,0.0002895773,0.996967,0.000003245819,0.00001655043,0.001024374,0.0002181554,0.00008486475,0.001222656,0.000007125961,0.0001620592,0.000001760156],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9997302,0.0001178743,0.00003898591,0.000001771973,6.755247e-7,0.000004720559,0.00002647313,0.000001070942,0.00007812875],"genre_scores_gemma":[0.9995126,0.00008816645,0.0001341734,0.000006590336,0.00000263182,0.000007827599,0.0001088866,8.270679e-7,0.000138383],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00099352,"threshold_uncertainty_score":0.002262771,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008793447324185862,"score_gpt":0.314211137609034,"score_spread":0.3054176902848481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}